Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 2/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | PAK4 | O96013 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | PRKACA | P17612 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | LTK | P29376 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69393 | 0.92 | NR4A2 (0.44) | CNR2NR4A2CREBBPPIM1MAP2K1 | |
| SCHEMBL257660 | 0.85 | CNR2 (0.40) | CNR2NR4A2CREBBPPIM1MAP2K1 | |
| SCHEMBL27820698 | 0.85 | CNR2 (0.42) | CNR2NR4A2CREBBPPIM1MAP2K1 | |
| SCHEMBL27820699 | 0.82 | NR4A2 (0.43) | CNR2NR4A2CREBBPPIM1MAP2K1 | |
| SCHEMBL28816343 | 0.82 | ALDH1A1 (0.45) | CNR2NR4A2CREBBPLMNAKDM4E | |
| SCHEMBL5004910 | 0.81 | PBRM1 (0.39) | PIM1MAP2K1DAPK3JAK2PRKD3 | |
| SCHEMBL29955321 | 0.79 | KEAP1 (0.38) | PIM1MAP2K1DAPK3JAK2PRKD3 | |
| SCHEMBL27906710 | 0.79 | LMNA (0.42) | CNR2NR4A2CREBBPPIM1MAP2K1 | |
| SCHEMBL2937272 | 0.76 | CA12 (0.47) | CNR2NR4A2CREBBPTSHRLMNA | |
| SCHEMBL29158222 | 0.76 | CSNK1A1 (0.40) | PIM1MAP2K1DAPK3JAK2PRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008055068-A2 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2008-05-08 | — | — | WO | disclosed |