Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22798569 | 1.00 | POLB (0.44) | POLBATMLMNASMN1; SMN2CA12 | |
| SCHEMBL670164 | 0.92 | POLB (0.43) | POLBATMLMNASMN1; SMN2CA12 | |
| SCHEMBL5567091 | 0.92 | POLB (0.43) | POLBATMLMNASMN1; SMN2CA12 | |
| SCHEMBL670165 | 0.92 | POLB (0.43) | POLBATMLMNASMN1; SMN2CA12 | |
| SCHEMBL6764378 | 0.86 | SYK (0.41) | POLBATMSMN1; SMN2NPC1RAB9A | |
| SCHEMBL8201443 | 0.82 | SMN1; SMN2 (0.37) | LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL6764370 | 0.81 | SYK (0.41) | POLBCA12CA1 | |
| SCHEMBL6764374 | 0.81 | SYK (0.41) | POLBCA12CA1 | |
| SCHEMBL9254620 | 0.81 | POLB (0.47) | POLBLMNASMN1; SMN2CA12CA1 | |
| SCHEMBL1728937 | 0.81 | POLB (0.50) | POLBLMNASMN1; SMN2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3753924-A1 | NEW TRICYCLIC 5-HT2 ANTAGONISTS | AnaMar AB (SE) | 2020-12-23 | — | — | EP | disclosed |
| WO-2000078723-A1 | PROCESS FOR THE PREPARATION OF BUTOXYCARBONYLIMINO COMPOUNDS AND INTERMEDIATES THEREFOR | GLAXO GROUP LIMITED (GB) | 2000-12-28 | — | — | WO | disclosed |