Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6989236 | 0.99 | FAAH (0.33) | FAAHMGLLIDO1 | |
| SCHEMBL6989173 | 0.85 | FAAH (0.35) | FAAHMGLLCHEK1 | |
| SCHEMBL6996361 | 0.84 | FAAH (0.35) | FAAHMGLLCHEK1 | |
| Hydrochloric Acid SCHEMBL6988527 | 0.84 | FAAH (0.35) | FAAHMGLLCHEK1 | |
| SCHEMBL6986977 | 0.84 | FAAH (0.35) | FAAHMGLLIDO1CHEK1 | |
| Hydrochloric Acid SCHEMBL6989175 | 0.83 | FAAH (0.34) | FAAHMGLLIDO1CHEK1 | |
| SCHEMBL6989241 | 0.82 | FAAH (0.33) | FAAHMGLL | |
| SCHEMBL6989250 | 0.81 | FAAH (0.33) | FAAHMGLL | |
| SCHEMBL6997384 | 0.80 | LMNA (0.32) | FAAHMGLL | |
| SCHEMBL6989881 | 0.79 | FAAH (0.41) | FAAHMGLLCHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6096771-A | ISOXAZOLE DERIVATIVES EXHIBITING EXCELLENT TYPE B AND TYPE A MONOAMINE OXIDASE INHIBITORY ACTIVITIES, THEREFORE USEFUL FOR PREVENTING PARKINSON'S DISEASE, DEPRESSION AND ALZHEIMER'S DISEASE | SANKYO COMPANY, LIMITED (JP) | 2000-08-01 | — | — | US | claimed |