Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 5/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PAM | P19021 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3593285 | 0.84 | MGLL (0.88) | MGLLALDH1A1MAPK1L3MBTL1PAM | |
| Benzene SCHEMBL9407299 | 0.75 | ALDH1A1 (0.65) | ALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL664857 | 0.75 | ALDH1A1 (0.65) | ALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL10839344 | 0.75 | MGLL (0.57) | MGLLTDP1 | |
| SCHEMBL6625857 | 0.74 | ALDH1A1 (0.66) | ALDH1A1MAPK1L3MBTL1TDP1PAM | |
| SCHEMBL2877979 | 0.73 | ALDH1A1 (0.63) | ALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL1140451 | 0.73 | TDP1 (0.53) | MGLLALDH1A1TDP1 | |
| SCHEMBL11445319 | 0.73 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL7759577 | 0.73 | MGLL (0.62) | MGLLALDH1A1TDP1 | |
| SCHEMBL32685092 | 0.73 | MGLL (0.51) | MGLLALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1007101-A2 | IMPROVEMENTS IN OR RELATING TO DIAGNOSTIC/THERAPEUTIC AGENTS | Marsden, John Christopher (GB) | 2000-06-14 | — | — | EP | disclosed |
| WO-1998018500-A2 | IMPROVEMENTS IN OR RELATING TO DIAGNOSTIC/THERAPEUTIC AGENTS | MARSDEN, JOHN, CHRISTOPHER (GB) | 1998-05-07 | — | — | WO | disclosed |