Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | CASP2 | P42575 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2629391 | 0.73 | EPHX2 (0.54) | BRD4CREBBPKMT2AEPHX2SMN1; SMN2 | |
| SCHEMBL7982185 | 0.71 | MEN1 (0.48) | BRD4CREBBPBRPF1KMT2AALDH1A1 | |
| SCHEMBL28552531 | 0.71 | AHR (0.50) | BRD4CREBBPKMT2AMAPTKDM4E | |
| SCHEMBL28517190 | 0.66 | PDGFRA (0.35) | BRD4CREBBPBRPF1KMT2AEPHX2 | |
| SCHEMBL8590983 | 0.66 | ACVR1 (0.44) | BRD4CREBBPKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL2629324 | 0.66 | BRD4 (0.65) | BRD4CREBBPBRPF1KMT2AEPHX2 | |
| SCHEMBL11071961 | 0.64 | DDB1 (0.50) | BRD4CREBBPBRPF1KMT2AEPHX2 | |
| SCHEMBL2279059 | 0.64 | GAA (0.51) | BRD4CREBBPKMT2AGAASMN1; SMN2 | |
| SCHEMBL20957514 | 0.62 | — | — | |
| SCHEMBL11066908 | 0.62 | BRD4 (0.45) | BRD4CREBBPBRPF1KMT2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6043239-A | N-SUBSTITUTED AZAHETEROCYCLIC CARBOXYLIC ACIDS AND ESTERS THEREOF IN WHICH A SUBSTITUTED ALKYL CHAIN FORMS PART OF THE N-SUBSTITUENT; TREATMENT OF PAINFUL, HYPERALGESIC AND/OR INFLAMMATORY CONDITIONS | NOVO NORDISK A/S (DK) | 2000-03-28 | — | — | US | disclosed |