Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 2/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3480587 | 0.79 | PDK2 (0.49) | — | |
| SCHEMBL3480536 | 0.78 | CYP11B2 (0.48) | — | |
| SCHEMBL3480534 | 0.78 | TDP1 (0.39) | — | |
| SCHEMBL8195793 | 0.75 | IDO1 (0.41) | MEN1KMT2A | |
| SCHEMBL17795211 | 0.74 | PDE3B (0.40) | PTGS2PTGS1KMO | |
| SCHEMBL21262444 | 0.73 | ENPP1 (0.43) | KDM4EMEN1KMT2A | |
| SCHEMBL10554279 | 0.73 | MAPT (0.43) | PTGS2PTGS1ADORA2AADORA1KDM4E | |
| SCHEMBL10556563 | 0.72 | PTGS2 (0.47) | PTGS2PTGS1ADORA2AADORA1KDM4E | |
| SCHEMBL12326172 | 0.72 | PTGS2 (0.53) | PTGS2PTGS1ADORA2AADORA1KMO | |
| SCHEMBL8194882 | 0.71 | PTGS2 (0.38) | PTGS2PTGS1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000018741-A2 | PYRAZOLE COMPOUNDS AS COX-2 INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-06 | — | — | WO | disclosed |