Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9082634 | 0.93 | SLC6A1 (0.48) | CHRNB2CHRNB4CHRNA3CHRNA4SLC6A1 | |
| SCHEMBL9083719 | 0.92 | SLC6A1 (0.52) | SLC6A1 | |
| SCHEMBL7611096 | 0.84 | SLC6A1 (0.60) | SLC6A1 | |
| Hydrochloric Acid SCHEMBL8187690 | 0.83 | SLC6A1 (0.59) | SLC6A1 | |
| SCHEMBL8206721 | 0.82 | SLC6A1 (0.61) | CHRNB2CHRNB4CHRNA3CHRNA4SLC6A1 | |
| SCHEMBL8202612 | 0.82 | SLC6A1 (0.61) | CHRNB2CHRNB4CHRNA3CHRNA4SLC6A1 | |
| SCHEMBL8206888 | 0.82 | SLC6A1 (0.61) | CHRNB2CHRNB4CHRNA3CHRNA4SLC6A1 | |
| SCHEMBL9085418 | 0.81 | CHRNB2 (0.47) | CHRNB2CHRNB4CHRNA3CHRNA4SLC6A1 | |
| SCHEMBL8202532 | 0.80 | SLC6A1 (0.60) | SLC6A1CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL9085967 | 0.79 | SLC6A1 (0.48) | CHRNB2CHRNB4CHRNA3CHRNA4SLC6A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738262-B1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK AS (DK) | 2000-04-19 | — | — | EP | claimed |