⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3468849 | 0.89 | — | — | |
| SCHEMBL19736674 | 0.85 | DNM1 (0.39) | — | |
| SCHEMBL24709143 | 0.81 | DNM1 (0.45) | — | |
| SCHEMBL16599984 | 0.78 | DNM1 (0.41) | — | |
| SCHEMBL28275311 | 0.77 | CYP3A4 (0.30) | — | |
| SCHEMBL2495712 | 0.75 | — | — | |
| SCHEMBL12250249 | 0.75 | — | — | |
| SCHEMBL16854579 | 0.75 | CYP3A4 (0.36) | — | |
| SCHEMBL10436478 | 0.74 | — | — | |
| SCHEMBL12178191 | 0.74 | ADRB2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9585875-B2 | TRPM8 antagonists | DOMPÉ FARMACEUTICI S.P.A. (IT) | 2017-03-07 | — | — | US | disclosed |
| US-8580832-B2 | Substituted phenoxy aminothiazolones as estrogen related receptor-α modulators | JANSSEN PHARMACEUTICA N.V. (BE) | 2013-11-12 | — | — | US | disclosed |
| EP-0673956-B1 | Binder for coating materials containing dispersed inorganic powder, coating material containing dispersed inorganic powder, and magnetic recording medium | NIPPON ZEON CO (JP) | 2000-01-05 | — | — | EP | disclosed |
| US-5607772-A | POLYURETHANE HAVING TERMINAL EPOXY GROUPS | NIPPON ZEON CO., LTD. (JP) | 1997-03-04 | — | — | US | disclosed |
| EP-0673956-A1 | Binder for coating materials containing dispersed inorganic powder, coating material containing dispersed inorganic powder, and magnetic recording medium | NIPPON ZEON CO., LTD. (JP) | 1995-09-27 | — | — | EP | disclosed |
| US-4784913-A | SUPPORT WITH VINYL CHLORIDE RESIN WITH CATIONIC AMMONIUM GROUPS | NIPPON ZEON CO., LTD. (JP) | 1988-11-15 | — | — | US | disclosed |