SCHEMBL8201776

SCHEMBL8201776

CCCC[Si](C)(C)CNC(=O)C(F)(F)F

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.55
ALDH1A1 P00352 1/20 0.45
POLB P06746 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
CA3 P07451 2/20 0.40
CA5A P35218 2/20 0.40
CA5B Q9Y2D0 2/20 0.40
CA12 O43570 1/20 0.40
CA2 P00918 1/20 0.40
CA4 P22748 1/20 0.40
CA6 P23280 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40
CA14 Q9ULX7 1/20 0.40
FAAH O00519 8/20 0.38
CES1 P23141 6/20 0.37
CES2 O00748 5/20 0.37
CYP1A2 P05177 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3647762 0.76 EPHX1 (0.52) EPHX1ALDH1A1POLBSMN1; SMN2MEN1
SCHEMBL2736707 0.74 EPHX1 (0.84) EPHX1ALDH1A1POLBSMN1; SMN2MEN1
SCHEMBL11663788 0.73 EPHX1 (0.53) EPHX1ALDH1A1POLBSMN1; SMN2MEN1
SCHEMBL1389225 0.72 EPHX1 (0.96) EPHX1ALDH1A1POLBSMN1; SMN2MEN1
SCHEMBL13010044 0.71 EPHX1 (1.00) EPHX1ALDH1A1POLBSMN1; SMN2MEN1
SCHEMBL9986495 0.71 ALDH1A1 (0.45) EPHX1ALDH1A1POLBSMN1; SMN2MEN1
SCHEMBL10688529 0.71 EPHX1 (1.00) EPHX1ALDH1A1POLBSMN1; SMN2MEN1
SCHEMBL7716931 0.71 EPHX1 (1.00) EPHX1ALDH1A1POLBSMN1; SMN2MEN1
SCHEMBL10690536 0.71 EPHX1 (1.00) EPHX1ALDH1A1POLBSMN1; SMN2MEN1
SCHEMBL10683800 0.71 EPHX1 (1.00) EPHX1ALDH1A1POLBSMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109307728-A The novel internal standard compound of amino acid, organic acid or phosphoric acid sugar metabolite in test sample 华东理工大学 2019-02-05 CN disclosed
EP-1021388-A1 PHOSPHORYLATION PROCESS AND CATALYST PERSTORP AB (SE) 2000-07-26 EP disclosed
WO-1997034853-A1 PHOSPHORYLATION PROCESS AND CATALYST PERSTORP AB (SE) 1997-09-25 WO disclosed