SCHEMBL9986495

SCHEMBL9986495

CC(C)(C)[Si](C)(C)CNC(=O)C(F)(F)F

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.45
POLB P06746 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
EPHX1 P07099 1/20 0.41
CA3 P07451 2/20 0.39
CA5A P35218 2/20 0.39
CA5B Q9Y2D0 2/20 0.39
CA2 P00918 2/20 0.39
CA14 Q9ULX7 2/20 0.39
CA12 O43570 1/20 0.39
CA4 P22748 1/20 0.39
CA6 P23280 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8201776 0.71 EPHX1 (0.55) ALDH1A1POLBSMN1; SMN2MEN1KMT2A
SCHEMBL8071669 0.69 ALDH1A1 (0.52) ALDH1A1POLBSMN1; SMN2MEN1KMT2A
SCHEMBL1387208 0.67
SCHEMBL919299 0.67 CA2 (0.40) ALDH1A1POLBSMN1; SMN2MEN1KMT2A
SCHEMBL24687426 0.66 ALDH1A1 (0.62) ALDH1A1POLBSMN1; SMN2MEN1KMT2A
SCHEMBL13861685 0.66 ALDH1A1 (0.79) ALDH1A1POLBSMN1; SMN2MEN1KMT2A
Hydrochloric Acid SCHEMBL29893277 0.66 ALDH1A1 (0.54) ALDH1A1POLBSMN1; SMN2MEN1KMT2A
SCHEMBL27098286 0.66
SCHEMBL22645717 0.65 EPHX1 (0.36) ALDH1A1POLBSMN1; SMN2MEN1KMT2A
SCHEMBL12927101 0.65 ALDH1A1 (0.60) ALDH1A1POLBSMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108956819-A A kind of method that gas phase-mass spectrometry detects food-borne pyrroles's element 广东食品药品职业学院 2018-12-07 CN claimed
EP-3231436-B1 PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF METABOLIC DISEASE, COMPRISING BACTEROIDES ACIDIFACIENS AS EFFECTIVE INGREDIENT GI BIOME (KR) 2020-03-11 EP disclosed
US-20190328797-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING METABOLIC DISEASES, COMPRISING BACTEROIDES ACIDIFACIENS AS ACTIVE INGREDIENT GI BIOME (KR) 2019-10-31 US disclosed
US-10369174-B2 Pharmaceutical composition for preventing or treating metabolic diseases, comprising bacteroides acidifaciens as active ingredient GI BIOME (KR) 2019-08-06 US disclosed
CN-109641890-A Isocitric dehydrogenase (IDH) inhibitor 上海迈同生物科技有限公司 2019-04-16 CN disclosed
CN-108956819-A A kind of method that gas phase-mass spectrometry detects food-borne pyrroles's element 广东食品药品职业学院 2018-12-07 CN disclosed
CN-108314621-A A method of manufacture long chain diacid monoesters 斯福瑞(南通)制药有限公司 2018-07-24 CN disclosed
CN-108135925-A GLYCAN COMPOSITIONS AND USES THEREOF 卡莱多生物科技有限公司 2018-06-08 CN disclosed
US-20170333492-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING METABOLIC DISEASES, COMPRISING BACTEROIDES ACIDIFACIENS AS ACTIVE INGREDIENT GI BIOME (KR) 2017-11-23 US disclosed
EP-3231436-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF METABOLIC DISEASE, COMPRISING BACTEROIDES ACIDIFACIENS AS EFFECTIVE INGREDIENT The Asan Foundation (KR) 2017-10-18 EP disclosed
US-20130244311-A1 USE OF PSYCHROPHILIC ANAEROBIC DIGESTION IN SEQUENCING BATCH REACTOR FOR DEGRADATION OF PRIONS BIO-TERRE SYSTEMS INC. (CA) 2013-09-19 US disclosed
US-8486688-B2 Use of psychrophilic anaerobic digestion in sequencing batch reactor for degradation of prions BIO-TERRE SYSTEMS INC. (CA) 2013-07-16 US disclosed
EP-2582835-A1 USE OF PSYCHROPHILIC ANAEROBIC DIGESTION IN SEQUENCING BATCH REACTOR FOR DEGRADATION OF PRIONS Her Majesty The Queen In Right Of Canada, As Represented By the Minister of Agriculture and Agri-Food (CA) 2013-04-24 EP disclosed
US-20110312099-A1 USE OF PSYCHROPHILIC ANAEROBIC DIGESTION IN SEQUENCING BATCH REACTOR FOR DEGRADATION OF PRIONS BIO-TERRE SYSTEMS INC. (CA) 2011-12-22 US disclosed
WO-2011156885-A1 USE OF PSYCHROPHILIC ANAEROBIC DIGESTION IN SEQUENCING BATCH REACTOR FOR DEGRADATION OF PRIONS HER MAJESTY THE QUEEN IN RIGHT OF CANADA, AS REPRESENTED BY THE MINISTER OF AGRICULTURE AND AGRI-FOOD (CA) 2011-12-22 WO disclosed