Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A1 | P30531 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 3/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8203622 | 0.89 | CHRNB2 (0.47) | SLC6A1 | |
| SCHEMBL8206721 | 0.88 | SLC6A1 (0.61) | SLC6A1CHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL8202612 | 0.88 | SLC6A1 (0.61) | SLC6A1CHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL8202368 | 0.87 | SLC6A1 (0.57) | SLC6A1CHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL8206888 | 0.86 | SLC6A1 (0.61) | SLC6A1DRD2HTR7 | |
| SCHEMBL7604123 | 0.85 | SLC6A1 (0.63) | SLC6A1CHRM1 | |
| Hydrochloric Acid SCHEMBL8196530 | 0.84 | SLC6A1 (0.62) | SLC6A1 | |
| SCHEMBL7472521 | 0.83 | CHRM5 (0.41) | HRH1CHRM1CHRM5DRD2HTR2A | |
| SCHEMBL7813228 | 0.82 | CHRNB2 (0.56) | SLC6A1 | |
| SCHEMBL7815736 | 0.82 | CHRNB2 (0.56) | SLC6A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738262-B1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK AS (DK) | 2000-04-19 | — | — | EP | claimed |