Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6161752 | 0.77 | KDM4E (0.34) | KDM4EALDH1A1TSHR | |
| SCHEMBL2522189 | 0.75 | KDM4E (0.38) | KDM4EALDH1A1TSHRHRH1KCNH2 | |
| SCHEMBL3160945 | 0.68 | KDM4E (0.35) | KDM4EALDH1A1TSHRHRH1KCNH2 | |
| SCHEMBL7280997 | 0.68 | KDM4E (0.35) | KDM4EALDH1A1TSHR | |
| SCHEMBL1617758 | 0.68 | DPP4 (0.45) | KCNH2 | |
| SCHEMBL1617776 | 0.68 | DPP4 (0.45) | KCNH2 | |
| SCHEMBL2926049 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL6165347 | 0.67 | DPP4 (0.44) | KCNH2 | |
| Hydrochloric Acid SCHEMBL6165352 | 0.67 | DPP4 (0.44) | KCNH2 | |
| SCHEMBL3842916 | 0.67 | KDM4E (0.34) | KDM4EALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6107329-A | HYPOTENSIVE AGENTS; CARDIOVASCULAR DISORDERS | PFIZER, INC. (US) | 2000-08-22 | — | — | US | disclosed |
| WO-1996039384-A1 | SUBSTITUTED N-(INDOLE-2-CARBONYL)-GLYCINAMIDES AND DERIVATIVES AS GLYCOGEN PHOSPHORYLASE INHIBITORS | PFIZER, INC. (US) | 1996-12-12 | — | — | WO | disclosed |