SCHEMBL820212

SCHEMBL820212

CCOCC(C(=O)Cl)(c1ccccc1)C(C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.39
HIF1A Q16665 1/20 0.39
MAPK1 P28482 1/20 0.36
POLB P06746 2/20 0.36
KMT2A Q03164 2/20 0.36
MAPT P10636 1/20 0.36
CHRM2 P08172 1/20 0.35
CHRM4 P08173 1/20 0.35
CHRM5 P08912 1/20 0.35
CHRM1 P11229 1/20 0.35
CHRM3 P20309 1/20 0.35
KCNN4 O15554 1/20 0.35
ALDH1A1 P00352 3/20 0.35
CYP1A2 P05177 1/20 0.34
ALOX15 P16050 1/20 0.34
HDAC3 O15379 1/20 0.34
HDAC4 P56524 1/20 0.34
HDAC1 Q13547 1/20 0.34
HDAC7 Q8WUI4 1/20 0.34
HDAC2 Q92769 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL818978 0.84 KCNN4 (0.41) CYP2C19HIF1AMAPK1KMT2AMAPT
SCHEMBL819785 0.74 CACNA1G (0.39) CYP2C19HIF1AKMT2AMAPTCHRM3
SCHEMBL28205550 0.73 CYP2C19 (0.43) CYP2C19HIF1AMAPK1POLBKMT2A
SCHEMBL818876 0.72 GRIN2D (0.37) CYP2C19HIF1AMAPTCHRM2CHRM1
SCHEMBL29097238 0.71 KMT2A (0.42) CYP2C19HIF1AMAPK1POLBKMT2A
SCHEMBL3268588 0.71 HIF1A (0.47) CYP2C19HIF1AKMT2AMAPTKCNN4
SCHEMBL24781345 0.70 ALDH1A1 (0.40) CYP2C19HIF1AMAPK1POLBKMT2A
SCHEMBL11497301 0.70 MAPK1 (0.48) CYP2C19HIF1AMAPK1POLBKMT2A
SCHEMBL4557326 0.70 MAPT (0.44) CYP2C19HIF1AKMT2AMAPTCHRM2
Ether SCHEMBL27795509 0.69 CYP2C19 (0.46) CYP2C19HIF1AMAPK1POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8288488-B2 Process for producing solid catalyst component for olefin polymerization SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-16 US disclosed
CN-102336848-A Process for producing solid catalyst component for olefin polymerization SUMITOMO CHEMICAL CO 2012-02-01 CN disclosed
US-20110269929-A1 PROCESS FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-03 US disclosed
US-20110269928-A1 PROCESS FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-03 US disclosed