Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6465281 | 0.91 | MEN1 (0.41) | — | |
| Hydrochloric Acid SCHEMBL8854007 | 0.88 | KDM4E (0.30) | — | |
| Hydrochloric Acid SCHEMBL2389150 | 0.88 | KDM4E (0.30) | — | |
| Hydrochloric Acid SCHEMBL2114633 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL2117251 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL17743563 | 0.85 | MEN1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL18420424 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL2115084 | 0.84 | POLB (0.33) | — | |
| Hydrochloric Acid SCHEMBL18420709 | 0.84 | CYP19A1 (0.36) | — | |
| Hydrochloric Acid SCHEMBL18690028 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7662895-B2 | comprising polypropylene which is produced in presence of a metallocene transition metal catalyst and an activator; peak melting point temperature below about 110 degrees C., a tensile set of 40% or less, and greater than or equal to about 60% [r]dyads | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2010-02-16 | — | — | US | claimed |
| US-6982236-B2 | Process to polymerize olefins | UNIVATION TECHNOLOGIES, LLC (US) | 2006-01-03 | — | — | US | claimed |
| US-6897273-B2 | Catalyst composition, method of polymerization and polymer therefrom | UNIVATION TECHNOLOGIES, LLC (US) | 2005-05-24 | — | — | US | claimed |
| EP-1392743-A2 | CATALYST COMPOSITION, METHOD OF POLYMERIZATION AND POLYMER THEREFROM | Univation Technologies LLC (US) | 2004-03-03 | — | — | EP | claimed |
| US-20040039138-A1 | Catalyst preparation method | WENZEL TIMOTHY T (US) | 2004-02-26 | — | — | US | claimed |
| US-6656866-B2 | Metallocene and non-metallocene, homogeneous catalysts, particularly for use in the economical gas and slurry phase processes; spray dried olefin polymerization catalysts | UNIVATION TECHNOLOGIES, LLC | 2003-12-02 | — | — | US | claimed |
| US-20030207762-A9 | CATALYST PREPARATION METHOD | UNIVATION TECHNOLOGIES, LLC | 2003-11-06 | — | — | US | claimed |
| EP-1358216-A2 | START-UP PROCEDURE FOR MULTIPLE CATALYST POLYMERIZATION SYSTEMS | Univation Technologies LLC (US) | 2003-11-05 | — | — | EP | claimed |
| US-6620894-B2 | Calibration; using coordination catalyst | UNIVATION TECHNOLOGIES, LLC | 2003-09-16 | — | — | US | claimed |
| US-20020132937-A1 | Start-up procedure for multiple catalyst polymerization systems | UNIVATION TECHNOLOGIES, LLC | 2002-09-19 | — | — | US | claimed |
| WO-2002050127-A2 | START-UP PROCEDURE FOR MULTIPLE CATALYST POLYMERIZATION SYSTEMS | UNIVATION TECHNOLOGIES, LLC (US) | 2002-06-27 | — | — | WO | claimed |
| WO-2002046250-A2 | CATALYST COMPOSITION, METHOD OF POLYMERIZATION AND POLYMER THEREFROM | UNIVATION TECHNOLOGIES, LLC (US) | 2002-06-13 | — | — | WO | claimed |
| US-RE36103-E | Process for the preparation of a syndiotactic polyolefin and catalyst therefor | TARGOR GMBH (DE) | 1999-02-16 | — | — | US | claimed |
| EP-0615981-B1 | Supported catalyst system, its preparation and its use in olefin polymerisation | TARGOR GMBH (DE) | 1998-05-06 | — | — | EP | claimed |
| EP-0485893-B1 | Bulk polymerisation with metallocene catalyst for the preparation of cycloolefin polymers | TICONA GMBH (DE) | 1998-04-22 | — | — | EP | claimed |
| EP-0610852-B1 | Process for preparing cyclo-olefin polymers | HOECHST AG (DE) | 1997-05-07 | — | — | EP | claimed |
| US-5545829-A | Process for preparing cycloolefin copolymers | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-08-13 | — | — | US | claimed |
| EP-0387691-B1 | Process for preparing a syndiotactic polyolefin | HOECHST AG (DE) | 1995-06-28 | — | — | EP | claimed |
| US-5371158-A | Bulk polymerization using specific metallocene catalysts for the preparation of cycloolefin polymers | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-12-06 | — | — | US | claimed |
| US-5132381-A | Aluminoxane, Hafnium Metallocene | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-07-21 | — | — | US | claimed |