SCHEMBL820229

SCHEMBL820229

CCc1[c]c(C(C)C)ccc1

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.30
GABRG2 P18507 1/20 0.30
GABRB3 P28472 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2776672 0.83 TSHR (0.35)
SCHEMBL820644 0.83
SCHEMBL27541092 0.81 LOXL2 (0.31)
SCHEMBL1777957 0.81 GABRA1 (0.38) GABRA1
SCHEMBL819202 0.80 KCNH2 (0.32)
SCHEMBL177278 0.78 GABRA1 (0.38) GABRA1
SCHEMBL60696 0.78 GABRA1 (0.38) GABRA1GABRG2GABRB3
SCHEMBL8576128 0.77 KCNH2 (0.42)
SCHEMBL1777500 0.77 KCNH2 (0.42)
SCHEMBL27844043 0.76 GABRA1 (0.36) GABRA1GABRG2GABRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 187 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109563110-B Quinolinyldiamido transition metal complexes, their production and use 埃克森美孚化学专利公司 2021-08-20 CN claimed
EP-3478694-B9 QUINOLINYLDIAMIDO TRANSITION METAL COMPLEXES, PRODUCTION AND USE THEREOF EXXONMOBIL CHEMICAL PATENTS INC (US) 2021-08-04 EP claimed
US-10927196-B2 Long chain branched polypropylene via polymerization with aluminum vinyl transfer agent EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-02-23 US claimed
EP-3478694-B1 QUINOLINYLDIAMIDO TRANSITION METAL COMPLEXES, PRODUCTION AND USE THEREOF EXXONMOBIL CHEMICAL PATENTS INC (US) 2020-12-09 EP claimed
US-10815318-B2 Quinolinyldiamido transition metal complexes, production and use thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2020-10-27 US claimed
US-10562987-B2 Polymers produced via use of quinolinyldiamido transition metal complexes and vinyl transfer agents EXXONMOBIL CHEMICAL PATENTS INC. (US) 2020-02-18 US claimed
US-20190177449-A1 Quinolinyldiamido Transition Metal Complexes, Production and Use Thereof EXXONMOBIL CHEMICAL PATENTS INC. 2019-06-13 US claimed
EP-3478694-A1 QUINOLINYLDIAMIDO TRANSITION METAL COMPLEXES, PRODUCTION AND USE THEREOF ExxonMobil Chemical Patents Inc. (US) 2019-05-08 EP claimed
CN-109563110-A Quinolyl diamino transition metal complex, production and purposes 埃克森美孚化学专利公司 2019-04-02 CN claimed
US-10208140-B2 Quinolinyldiamido transition metal complexes, production and use thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2019-02-19 US claimed
WO-2018160276-A1 POLYMERS PRODUCED VIA USE OF QUINOLINYLDIAMIDO TRANSITION METAL COMPLEXES AND VINYL TRANSFER AGENTS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2018-09-07 WO claimed
US-20180134816-A1 Polymers Produced via Use of Quinolinyldiamido Transition Metal Complexes and Vinyl Transfer Agents EXXONMOBIL CHEMICAL PATENTS INC. 2018-05-17 US claimed
US-20180002352-A1 Quinolinyldiamido Transition Metal Complexes, Production and Use Thereof EXXONMOBIL CHEMICAL PATENTS INC. 2018-01-04 US claimed
WO-2018005201-A1 QUINOLINYLDIAMIDO TRANSITION METAL COMPLEXES, PRODUCTION AND USE THEREOF EXXONMOBIL CHEMICAL PATENTS INC. (US) 2018-01-04 WO claimed
US-20090186876-A1 Pyridine Analogues II ASTRAZENECA AB (SE) 2009-07-23 US claimed
CN-101479256-A New pyridine analogues ASTRAZENECA AB (SE) 2009-07-08 CN claimed
EP-2041111-A1 NEW PYRIDINE ANALOGUES AstraZeneca AB (SE) 2009-04-01 EP claimed
WO-2008002247-A1 NEW PYRIDINE ANALOGUES ASTRAZENECA AB (SE) 2008-01-03 WO claimed
US-20070244088-A1 New Pyridine Analogues II ASTRAZENECA AB (SE) 2007-10-18 US claimed
US-5807864-A INCREASING HIGH DENSITY LIPOPROTEIN LEVELS AMERICAN HOME PRODUCTS CORPORATION (US) 1998-09-15 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10208140-B2 Quinolinyldiamido transition metal complexes, production and use thereof PARN, PARG, PICALM GABRA1 3710/4885GABRG2 3594/4885GABRB3 3400/4885
US-20180002352-A1 Quinolinyldiamido Transition Metal Complexes, Production and Use Thereof PARN, PARG, PICALM GABRA1 3710/4885GABRG2 3594/4885GABRB3 3400/4885
US-20070244088-A1 New Pyridine Analogues II P2RY12, P2RY1, P2RY11 GABRA1 1100/4885GABRG2 1174/4885GABRB3 1976/4885
US-10815318-B2 Quinolinyldiamido transition metal complexes, production and use thereof PARN, PARG, PICALM GABRA1 3710/4885GABRG2 3594/4885GABRB3 3400/4885
US-20190177449-A1 Quinolinyldiamido Transition Metal Complexes, Production and Use Thereof PARN, PARG, PICALM GABRA1 3710/4885GABRG2 3594/4885GABRB3 3400/4885
US-20090186876-A1 Pyridine Analogues II P2RY12, P2RY11, P2RY6 GABRA1 2179/4885GABRG2 2601/4885GABRB3 2404/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.