SCHEMBL8202370

SCHEMBL8202370

COS(=O)(=O)c1c(F)cccc1F

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PKM P14618 7/20 0.45
PKLR P30613 2/20 0.45
HTR6 P50406 2/20 0.36
GAA P10253 1/20 0.36
MAPK1 P28482 1/20 0.36
KMT2A Q03164 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
PTGES2 Q9H7Z7 1/20 0.35
CES2 O00748 1/20 0.34
CES1 P23141 1/20 0.34
PSIP1 O75475 1/20 0.34
SLC40A1 Q9NP59 1/20 0.33
KEAP1 Q14145 1/20 0.33
IKBKB O14920 1/20 0.33
KAT6A Q92794 1/20 0.33
KRAS P01116 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15352520 0.86 PKM (0.43) PKMPKLRGAASMN1; SMN2
SCHEMBL15353121 0.86 PKM (0.39) PKMPKLRHTR6GAAMAPK1
SCHEMBL8854502 0.80 KCNN4 (0.36) PKMPKLRHTR6PTGES2SLC40A1
SCHEMBL16467704 0.77 AGTR1 (0.34) PKMPTGES2CES2CES1
SCHEMBL16467626 0.77 PKM (0.45) PKMPKLRHTR6PTGES2CES2
SCHEMBL14114762 0.77 PKM (0.41) PKMPKLRHTR6CES2CES1
SCHEMBL6115202 0.76 PKM (0.44) PKMPKLRHTR6CES2CES1
SCHEMBL8761324 0.76 KMT2A (0.45) HTR6KMT2ASMN1; SMN2KAT6A
SCHEMBL15353308 0.75 MAPT (0.38) KMT2ASMN1; SMN2CES1KEAP1
SCHEMBL15352172 0.74 CCR4 (0.46) HTR6GAAMAPK1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110635167-B Nonaqueous electrolyte solution, battery containing same, and electric vehicle 比亚迪股份有限公司 2021-04-20 CN claimed
CN-110635167-A Nonaqueous electrolyte solution, battery containing same, and electric vehicle 比亚迪股份有限公司 2019-12-31 CN claimed
CN-110635167-B Nonaqueous electrolyte solution, battery containing same, and electric vehicle 比亚迪股份有限公司 2021-04-20 CN disclosed
EP-2841429-B1 TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES SUMITOMO CHEMICAL CO (JP) 2020-10-21 EP disclosed
CN-110635167-A Nonaqueous electrolyte solution, battery containing same, and electric vehicle 比亚迪股份有限公司 2019-12-31 CN disclosed
US-9565856-B2 Tetrazolinone compounds and its use as pesticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-02-14 US disclosed
US-20150051171-A1 TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-02-19 US disclosed
WO-2008076046-A1 NOVEL 2-AMINO-5, 5-DIARYL-IMIDAZOL-4-ONES ASTRAZENECA AB (SE) 2008-06-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150051171-A1 TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES CBR3, CYCS, CBR1 PKM 1646/4885PKLR 2338/4885HTR6 2717/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.