Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 2/20 | 0.48 |
| ▸ | CTSK | P43235 | 3/20 | 0.48 |
| ▸ | TACR1 | P25103 | 2/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | TDO2 | P48775 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24448342 | 1.00 | PPARA (0.51) | PPARAPPARGFOLH1CASP1CTSK | |
| SCHEMBL8195832 | 0.90 | KYNU (0.55) | CASP1CTSKCTSLCTSBCTSS | |
| SCHEMBL28836239 | 0.90 | PPARA (0.57) | PPARAPPARGFOLH1CASP1CTSK | |
| SCHEMBL13613766 | 0.90 | PPARA (0.57) | PPARAPPARGFOLH1CASP1CTSK | |
| SCHEMBL1024175 | 0.86 | PPARA (0.64) | PPARAPPARGFOLH1CASP1CTSK | |
| SCHEMBL28595041 | 0.86 | PPARA (0.64) | PPARAPPARGFOLH1CASP1CTSK | |
| SCHEMBL1171673 | 0.86 | PPARA (0.64) | PPARAPPARGFOLH1CASP1CTSK | |
| SCHEMBL24459326 | 0.85 | ATM (0.50) | CTSKCTSLCTSBCTSSCTRB1 | |
| SCHEMBL924114 | 0.84 | PPARA (0.53) | PPARAPPARGCASP1CTSKTACR1 | |
| SCHEMBL21837546 | 0.84 | PPARA (0.58) | PPARAPPARGFOLH1CASP1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022109363-A1 | NOVEL SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. (US) | 2022-05-27 | — | — | WO | disclosed |
| EP-4001279-A1 | NOVEL SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS | Enanta Pharmaceuticals, Inc. (US) | 2022-05-25 | — | — | EP | disclosed |
| CN-114524821-A | Novel spiropyrrolidine derived antiviral drugs | 英安塔制药有限公司 | 2022-05-24 | — | — | CN | disclosed |
| EP-0669936-B1 | MERCAPTOACETYLAMIDE BICYCLIC LACTAM DERIVATIVES USEFUL AS INHIBITORS OF ENKEPHALINASE AND ACE | MERRELL PHARMA INC (US) | 2000-11-22 | — | — | EP | disclosed |
| US-5635502-A | ANALGESIC, HYPOTENSIVE AGENT, DIURETIC, AND USED FOR TREATMENT OF CONGESTIVE HEART FAILURE OR IRRITABLE BOWEL SYNDROME | MERRELL PHARMACEUTICALS INC. (US) | 1997-06-03 | — | — | US | disclosed |