Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.34 |
| ▸ | TOP1 | P11387 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8189655 | 0.91 | L3MBTL1 (0.38) | RPS6KA1L3MBTL1BRD4CREBBPADRB1 | |
| SCHEMBL8197296 | 0.79 | BRD4 (0.39) | RPS6KA1L3MBTL1BRD4CREBBPADRB1 | |
| SCHEMBL8196981 | 0.78 | PARP1 (0.40) | RPS6KA1L3MBTL1BRD4CREBBPDDB1 | |
| SCHEMBL8201875 | 0.77 | NR3C2 (0.39) | ADRB1ADRB2PDE3BPDE3A | |
| SCHEMBL8195296 | 0.77 | BRD4 (0.43) | L3MBTL1BRD4CREBBPADRB1ADRB2 | |
| SCHEMBL8189703 | 0.77 | L3MBTL1 (0.41) | L3MBTL1BRD4CREBBP | |
| SCHEMBL8191691 | 0.77 | RPS6KA1 (0.42) | RPS6KA1L3MBTL1BRD4CREBBPADRB1 | |
| SCHEMBL8200742 | 0.73 | NR3C2 (0.50) | L3MBTL1BRD4CREBBPADRB1ADRB2 | |
| SCHEMBL13343842 | 0.70 | L3MBTL1 (0.39) | RPS6KA1L3MBTL1BRD4CREBBPPRMT5 | |
| SCHEMBL8189695 | 0.70 | ADRB2 (0.36) | ADRB1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063668-A1 | HETEROBICYCLIC METALLOPROTEASE INHIBITORS | ALANTOS PHARMACEUTICALS HOLDING, INC. (US) | 2008-05-29 | — | — | WO | disclosed |