SCHEMBL820278

SCHEMBL820278

N#CC1=Cc2ccccc2C1C#N

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 1/20 0.36
LMNA P02545 1/20 0.35
ATM Q13315 1/20 0.31
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
GPR84 Q9NQS5 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29152347 0.80 MEN1 (0.34)
SCHEMBL3550306 0.74 HTR2A (0.45) PIM1LMNAATMCA1CA2
SCHEMBL28728207 0.73 LMNA (0.36) LMNAGPR84
SCHEMBL8666304 0.71 EEF2K (0.49) TSHR
SCHEMBL15065080 0.71 LMNA (0.35) PIM1LMNAATM
SCHEMBL7874845 0.70
SCHEMBL13020958 0.70 PIM1 (0.50) PIM1ATMTSHR
SCHEMBL11038883 0.69 HPGD (0.44) LMNATSHR
SCHEMBL8019760 0.68 CUL4A (0.41) LMNA
SCHEMBL8012493 0.68 RAB9A (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2382241-B1 POLYMERS FUNCTIONALIZED WITH POLYCYANO COMPOUNDS BRIDGESTONE CORP (JP) 2016-11-23 EP claimed
US-8785566-B2 Polymers functionalized with polycyano compounds BRIDGESTONE CORPORATION (JP) 2014-07-22 US claimed
CN-122010979-A Organic micromolecular photovoltaic material based on benzopyrazine donor cores, and preparation method and application thereof 国家纳米科学中心 2026-05-12 CN disclosed
CN-114181229-B Organic micromolecular photovoltaic material based on benzopyrazine donor cores, and preparation method and application thereof 嘉兴禾浦光电科技有限公司 2023-11-03 CN disclosed
US-10081688-B2 Polymers functionalized with polycyano compounds BRIDGESTONE CORPORATION (JP) 2018-09-25 US disclosed
US-20170002112-A1 POLYMERS FUNCTIONALIZED WITH POLYCYANO COMPOUNDS BRIDGESTONE CORPORATION (JP) 2017-01-05 US disclosed
EP-2382241-B1 POLYMERS FUNCTIONALIZED WITH POLYCYANO COMPOUNDS BRIDGESTONE CORP (JP) 2016-11-23 EP disclosed
US-9447213-B2 Polymers functionalized with polycyano compounds BRIDGESTONE CORPORATION (JP) 2016-09-20 US disclosed
US-20140275403-A1 POLYMERS FUNCTIONALIZED WITH POLYCYANO COMPOUNDS BRIDGESTONE CORPORATION (JP) 2014-09-18 US disclosed
US-8785566-B2 Polymers functionalized with polycyano compounds BRIDGESTONE CORPORATION (JP) 2014-07-22 US disclosed
CN-102361888-B Polymers functionalized with polycyano compounds BRIDGESTONE CORP 2013-11-20 CN disclosed
CN-102361888-A Polymers functionalized with polycyano compounds BRIDGESTONE CORP 2012-02-22 CN disclosed
US-20110288200-A1 POLYMERS FUNCTIONALIZED WITH POLYCYANO COMPOUNDS BRIDGESTONE CORPORATION (JP) 2011-11-24 US disclosed
EP-2382241-A2 POLYMERS FUNCTIONALIZED WITH POLYCYANO COMPOUNDS Bridgestone Corporation (JP) 2011-11-02 EP disclosed
WO-2010085631-A2 POLYMERS FUNCTIONALIZED WITH POLYCYANO COMPOUNDS BRIDGESTONE CORPORATION (JP) 2010-07-29 WO disclosed