Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EEF2K | O00418 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | KDM1A | O60341 | 3/20 | 0.38 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CLK2 | P49760 | 1/20 | 0.36 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.36 |
| ▸ | MARK2 | Q7KZI7 | 1/20 | 0.36 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.36 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.36 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8019760 | 0.80 | CUL4A (0.41) | EEF2KKDM1AHTR2CHTR2BALDH1A1 | |
| SCHEMBL8012493 | 0.73 | RAB9A (0.39) | KDM1AHTR2CHTR2BMEN1KMT2A | |
| SCHEMBL8023485 | 0.71 | MAPT (0.44) | NPC1KDM1AALDH1A1KDM4EMEN1 | |
| SCHEMBL820278 | 0.71 | PIM1 (0.36) | TSHR | |
| SCHEMBL28728207 | 0.68 | LMNA (0.36) | EEF2KALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL15572213 | 0.66 | EEF2K (1.00) | EEF2KNPC1TSHRALDH1A1KDM4E | |
| SCHEMBL11038883 | 0.64 | HPGD (0.44) | TSHRALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL28773429 | 0.62 | KDM1A (0.50) | EEF2KKDM1AKDM1BHTR2CHTR2B | |
| SCHEMBL3213803 | 0.62 | TSHR (0.42) | TSHRALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL3213322 | 0.60 | ADORA2A (0.36) | NPC1TSHRALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877735-A1 | POLYCYCLIC COMPOUNDS | University of Strathclyde (GB) | 1998-11-18 | — | — | EP | disclosed |
| WO-1997019929-A1 | POLYCYCLIC COMPOUNDS | THE UNIVERSITY OF STRATHCLYDE (GB) | 1997-06-05 | — | — | WO | disclosed |