SCHEMBL8203374

SCHEMBL8203374

CO/C=C(/C(=O)O)c1ccccc1COC/C=N/N(C)Cc1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ABCC1 P33527 1/20 0.35
KDM4E B2RXH2 3/20 0.34
ALDH1A1 P00352 3/20 0.34
KMT2A Q03164 1/20 0.33
HPGD P15428 1/20 0.32
TSHR P16473 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8403377 0.72 IDO1 (0.42)
SCHEMBL7170181 0.72 KMT2A (0.49) KDM4EALDH1A1KMT2ATSHR
SCHEMBL8403381 0.72 IDO1 (0.42)
SCHEMBL8639304 0.71 KDM4E (0.47) KDM4EALDH1A1TSHR
SCHEMBL7752757 0.71 CYP1A2 (0.36) KDM4EALDH1A1
SCHEMBL7658115 0.70 HPGD (0.44) KDM4EALDH1A1HPGD
SCHEMBL7658118 0.70 HPGD (0.44) KDM4EALDH1A1HPGD
SCHEMBL29225957 0.69 KMT2A (0.47) KDM4EALDH1A1KMT2A
SCHEMBL5080478 0.69 ALDH1A1 (0.39) KDM4EALDH1A1KMT2AHPGDTSHR
SCHEMBL5998853 0.69 CA12 (0.36) KDM4EALDH1A1KMT2AHPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1021399-A2 FUNGICIDES WITH HYDROXIMIC AND HYDRAZONIC GROUPS AVENTIS CROPSCIENCE S.A. (FR) 2000-07-26 EP disclosed
WO-1998015512-A2 FUNGICIDES WITH HYDROXIMIC AND HYDRAZONIC GROUPS RHONE POULENC AGROCHIMIE (FR) 1998-04-16 WO disclosed