Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | CA1 | P00915 | 5/20 | 0.57 |
| ▸ | CA2 | P00918 | 5/20 | 0.57 |
| ▸ | CA9 | Q16790 | 5/20 | 0.57 |
| ▸ | CA12 | O43570 | 4/20 | 0.57 |
| ▸ | CA7 | P43166 | 4/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.50 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7422995 | 0.82 | LMNA (0.59) | LMNATSHRCA1CA2CA9 | |
| SCHEMBL27597208 | 0.81 | KDM4E (0.55) | LMNATSHRCA1CA2CA9 | |
| SCHEMBL16599381 | 0.81 | POLB (0.55) | LMNATSHRCA1CA2CA9 | |
| SCHEMBL1681296 | 0.81 | CA12 (0.54) | LMNATSHRCA1CA2CA9 | |
| SCHEMBL2684575 | 0.80 | KDM4E (0.53) | LMNATSHRCA1CA2CA9 | |
| SCHEMBL17824803 | 0.80 | KDM4E (0.53) | LMNATSHRCA1CA2CA9 | |
| SCHEMBL29453820 | 0.80 | KDM4E (0.53) | LMNATSHRCA1CA2CA9 | |
| SCHEMBL2085084 | 0.80 | ALDH1A1 (0.65) | LMNATSHRCA1CA2CA9 | |
| SCHEMBL6883362 | 0.79 | KDM4E (0.55) | LMNATSHRCA1CA2CA9 | |
| SCHEMBL28428886 | 0.79 | KDM4E (0.51) | LMNATSHRKDM4EPOLBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008038251-A2 | 3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2008-04-03 | — | — | WO | disclosed |