Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | MLKL | Q8NB16 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8208702 | 0.97 | MTNR1A (0.38) | MTNR1AMTNR1BCYP19A1EGFRMLKL | |
| SCHEMBL8196011 | 0.86 | CYP19A1 (0.34) | MTNR1AMTNR1BCYP19A1EGFRMLKL | |
| SCHEMBL3280740 | 0.84 | MTNR1A (0.38) | MTNR1AMTNR1BCYP19A1EGFRMLKL | |
| SCHEMBL8202811 | 0.84 | CYP19A1 (0.35) | MTNR1AMTNR1BCYP19A1EGFRMLKL | |
| SCHEMBL4510087 | 0.83 | MTNR1A (0.38) | MTNR1AMTNR1BCYP19A1EGFRMLKL | |
| SCHEMBL4492145 | 0.83 | MTNR1A (0.38) | MTNR1AMTNR1BCYP19A1EGFRMLKL | |
| SCHEMBL4492136 | 0.83 | MTNR1A (0.38) | MTNR1AMTNR1BCYP19A1EGFRMLKL | |
| SCHEMBL4499068 | 0.83 | MTNR1A (0.37) | MTNR1AMTNR1BCYP19A1EGFRMLKL | |
| SCHEMBL4499073 | 0.83 | MTNR1A (0.37) | MTNR1AMTNR1BCYP19A1EGFRMLKL | |
| SCHEMBL3280705 | 0.82 | MTNR1A (0.38) | MTNR1AMTNR1BCYP19A1EGFRMLKL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008043698-A1 | VINYLOGOUS ACIDS DERIVATIVES AS CHYMASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2008-04-17 | — | — | WO | disclosed |