Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | PGR | P06401 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SELP | P16109 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TLR4 | O00206 | 1/20 | 0.31 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.31 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alanine SCHEMBL11120060 | 0.94 | NOD2 (0.56) | NOD2MAPK1ESR1PGRHTR1A | |
| SCHEMBL342953 | 0.94 | NOD2 (0.57) | NOD2MAPK1ESR1PGRHTR1A | |
| SCHEMBL5270133 | 0.94 | NOD2 (0.57) | NOD2MAPK1ESR1PGRHTR1A | |
| SCHEMBL3229330 | 0.94 | NOD2 (0.57) | NOD2MAPK1ESR1PGRHTR1A | |
| Water SCHEMBL769017 | 0.93 | NOD2 (0.57) | NOD2MAPK1ESR1PGRHTR1A | |
| SCHEMBL4452390 | 0.88 | NOD2 (0.55) | NOD2MAPK1ESR1PGRHTR1A | |
| SCHEMBL4450131 | 0.88 | NOD2 (0.55) | NOD2MAPK1ESR1PGRHTR1A | |
| SCHEMBL10598564 | 0.88 | MAPK1 (0.57) | NOD2MAPK1ESR1PGRHTR1A | |
| SCHEMBL8539918 | 0.88 | NOD2 (0.55) | NOD2MAPK1ESR1PGRHTR1A | |
| SCHEMBL4446205 | 0.88 | NOD2 (0.55) | NOD2MAPK1ESR1PGRHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0831793-A4 | PROTEIN PARTICLES FOR THERAPEUTIC AND DIAGNOSTIC USE | HEMOSPHERE INC (US) | 2000-11-15 | — | — | EP | disclosed |
| EP-0831793-A1 | PROTEIN PARTICLES FOR THERAPEUTIC AND DIAGNOSTIC USE | HEMOSPHERE, INC. (US) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996039128-A1 | PROTEIN PARTICLES FOR THERAPEUTIC AND DIAGNOSTIC USE | HEMOSPHERE, INC. (US) | 1996-12-12 | — | — | WO | disclosed |