SCHEMBL820380

SCHEMBL820380

CC(=Cc1cccc(C)c1)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.66
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
KMT2A Q03164 2/20 0.48
LMNA P02545 2/20 0.48
KDM4E B2RXH2 1/20 0.48
MEN1 O00255 1/20 0.48
ALDH1A1 P00352 1/20 0.48
GAA P10253 1/20 0.48
MAPT P10636 1/20 0.48
SLC9A1 P19634 1/20 0.47
SLC9A3 P48764 1/20 0.47
SLC9A2 Q9UBY0 1/20 0.47
TDP1 Q9NUW8 2/20 0.47
TP53 P04637 1/20 0.47
TBXAS1 P24557 1/20 0.47
CASP3 P42574 1/20 0.46
SENP8 Q96LD8 1/20 0.46
SENP7 Q9BQF6 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7824296 1.00 AKR1C3 (0.66) AKR1C3NPC1RAB9ASMN1; SMN2KMT2A
SCHEMBL8746678 0.88 AKR1C3 (0.76) AKR1C3KMT2AKDM4EMEN1ALDH1A1
SCHEMBL8746676 0.88 AKR1C3 (0.76) AKR1C3KMT2AKDM4EMEN1ALDH1A1
SCHEMBL2439459 0.87 SLC9A1 (0.49) AKR1C3NPC1RAB9ASMN1; SMN2KMT2A
SCHEMBL27832652 0.87 SLC9A1 (0.49) AKR1C3NPC1RAB9ASMN1; SMN2KMT2A
SCHEMBL2439456 0.87 SLC9A1 (0.49) AKR1C3NPC1RAB9ASMN1; SMN2KMT2A
SCHEMBL13287355 0.87 SLC9A1 (0.49) AKR1C3NPC1RAB9ASMN1; SMN2KMT2A
SCHEMBL7441737 0.83 NPC1 (0.49) AKR1C3NPC1RAB9ASMN1; SMN2KMT2A
SCHEMBL9476015 0.82 GLO1 (0.50) AKR1C3NPC1RAB9ASMN1; SMN2KMT2A
SCHEMBL9476020 0.82 GLO1 (0.50) AKR1C3NPC1RAB9ASMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11708470-B2 Plastic substrate adhesion promoter with random copolymer PPG INDUSTRIES OHIO, INC. (US) 2023-07-25 US disclosed
EP-3656822-A1 COATINGS FOR PLASTIC SUBSTRATES PPG Industries Ohio, Inc. (US) 2020-05-27 EP disclosed
EP-3559060-A1 PLASTIC SUBSTRATE ADHESION PROMOTER WITH RANDOM COPOLYMER PPG Industries Ohio, Inc. (US) 2019-10-30 EP disclosed
US-10023761-B2 Coatings for plastic substrates PPG INDUSTRIES OHIO, INC. (US) 2018-07-17 US disclosed
WO-2018119038-A1 ADHESION PROMOTER PPG INDUSTRIES OHIO, INC. (US) 2018-06-28 WO disclosed
WO-2018119089-A1 PLASTIC SUBSTRATE ADHESION PROMOTER WITH RANDOM COPOLYMER PPG INDUSTRIES OHIO, INC. (US) 2018-06-28 WO disclosed
US-20180171170-A1 PLASTIC SUBSTRATE ADHESION PROMOTER WITH RANDOM COPOLYMER PPG INDUSTRIES OHIO, INC. 2018-06-21 US disclosed
US-20180171084-A1 ADHESION PROMOTER PPG INDUSTRIES OHIO, INC. 2018-06-21 US disclosed
EP-3313943-A1 COATINGS FOR PLASTIC SUBSTRATES PPG Industries Ohio, Inc. (US) 2018-05-02 EP disclosed
WO-2017003879-A1 COATINGS FOR PLASTIC SUBSTRATES PPG INDUSTRIES OHIO, INC. (US) 2017-01-05 WO disclosed
US-20160376465-A1 COATINGS FOR PLASTIC SUBSTRATES PPG INDUSTRIES OHIO, INC. 2016-12-29 US disclosed
US-20120010361-A1 CURABLE COMPOSITION AND CURED PRODUCT THEREOF SHOWA DENKO K.K. (JP) 2012-01-12 US disclosed
US-20100308273-A1 TERMINALLY MODIFIED ACRYLIC POLYMER AND METHOD FOR PRODUCING TERMINALLLY MODIFIED ACRYLIC POLYMER SEKISUI CHEMICAL CO., LTD. (JP) 2010-12-09 US disclosed
US-20070172772-A1 Microlens OMRON CORPORATION (JP) 2007-07-26 US disclosed
EP-1091958-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2001-04-18 EP disclosed
WO-2000001692-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2000-01-13 WO disclosed