Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.30 |
| ▸ | S100A4 | P26447 | 1/20 | 0.30 |
| ▸ | CDC25A | P30304 | 1/20 | 0.30 |
| ▸ | CDC25B | P30305 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27978353 | 0.79 | GPR3 (0.34) | GPR3HTR2A | |
| SCHEMBL4093574 | 0.77 | GPR3 (0.33) | GPR3 | |
| SCHEMBL6344393 | 0.75 | HTR2A (0.43) | ACHEBCHEGPR3HTR2ACHRM2 | |
| SCHEMBL8194753 | 0.74 | GPR3 (0.31) | GPR3 | |
| SCHEMBL8193731 | 0.70 | ACHE (0.33) | ACHEBCHEGPR3HTR2ACHRM2 | |
| SCHEMBL9075350 | 0.68 | HTR2A (0.45) | ACHEGPR3HTR2ACHRM2HTR1A | |
| SCHEMBL1941203 | 0.67 | GPR3 (0.38) | ACHEGPR3HTR2ACHRM2HTR1A | |
| SCHEMBL30387039 | 0.67 | ACHE (0.33) | ACHEBCHEGPR3HTR2ACHRM2 | |
| SCHEMBL8201868 | 0.67 | ACHE (0.33) | ACHEBCHEGPR3HTR2ACHRM2 | |
| SCHEMBL8204128 | 0.67 | CYP11B1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1062219-A1 | INTEGRATED PROCESS FOR PREPARATION OF DIENE COMPLEXES | THE DOW CHEMICAL COMPANY (US) | 2000-12-27 | — | — | EP | claimed |
| WO-1999046270-A1 | INTEGRATED PROCESS FOR PREPARATION OF DIENE COMPLEXES | THE DOW CHEMICAL COMPANY (US) | 1999-09-16 | — | — | WO | claimed |
| EP-1062219-A1 | INTEGRATED PROCESS FOR PREPARATION OF DIENE COMPLEXES | THE DOW CHEMICAL COMPANY (US) | 2000-12-27 | — | — | EP | disclosed |
| WO-1999046270-A1 | INTEGRATED PROCESS FOR PREPARATION OF DIENE COMPLEXES | THE DOW CHEMICAL COMPANY (US) | 1999-09-16 | — | — | WO | disclosed |