Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | GPR3 | P46089 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CDC25A | P30304 | 1/20 | 0.31 |
| ▸ | CDC25B | P30305 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6908083 | 0.98 | PBRM1 (0.33) | PBRM1TNKS2GPR3POLB | |
| SCHEMBL812546 | 0.79 | HTR2A (0.39) | GPR3POLBKMT2A | |
| Hydrochloric Acid SCHEMBL10180148 | 0.77 | HTR2A (0.38) | GPR3POLBKMT2A | |
| Hydrochloric Acid SCHEMBL6063882 | 0.72 | CDC25A (0.31) | CDC25ACDC25B | |
| SCHEMBL27709737 | 0.71 | GPR3 (0.37) | PBRM1TNKS2GPR3POLBCDC25A | |
| SCHEMBL8857182 | 0.70 | DRD2 (0.33) | PBRM1TNKS2GPR3POLBMEN1 | |
| SCHEMBL1941203 | 0.69 | GPR3 (0.38) | PBRM1TNKS2GPR3POLBCDC25A | |
| SCHEMBL6437792 | 0.68 | GPR3 (0.32) | GPR3POLBMEN1LMNAKMT2A | |
| SCHEMBL14277097 | 0.67 | MEN1 (0.40) | GPR3POLBMEN1LMNAKMT2A | |
| SCHEMBL28330081 | 0.67 | GPR3 (0.37) | PBRM1TNKS2GPR3POLBCDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6136993-A | CONTACTING IN GROUP 4 METAL COMPLEX OR ITS LEWIS BASE ADDUCT WITH METAL COMPLEX, RECOVERING RESULTING PRODUCT | THE DOW CHEMICAL COMPANY (US) | 2000-10-24 | — | — | US | claimed |
| US-6136993-A | CONTACTING IN GROUP 4 METAL COMPLEX OR ITS LEWIS BASE ADDUCT WITH METAL COMPLEX, RECOVERING RESULTING PRODUCT | THE DOW CHEMICAL COMPANY (US) | 2000-10-24 | — | — | US | disclosed |
| US-6084115-A | METAL DIENE-CONTAINING COMPLEXES BY REACTION WITH THE DIVALENT DERIVATIVE OF A BRIDGED BIDENTATE LIGAND; METALLOCENES; RACEMIC ISOMER USED TO PREPARE ISOTACTIC POLYOLEFINS, E.G., CRYSTALLINE POLYPROPYLENE. | THE DOW CHEMICAL COMPANY (US) | 2000-07-04 | — | — | US | disclosed |