Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | METAP1 | P53582 | 4/20 | 0.40 |
| ▸ | CES2 | O00748 | 4/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | TNF | P01375 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4899752 | 0.80 | MAPT (0.35) | METAP1MAOAACHE | |
| SCHEMBL1512741 | 0.75 | METAP1 (0.67) | BCHECES1METAP1MAOAACHE | |
| SCHEMBL12879668 | 0.73 | — | — | |
| SCHEMBL4900031 | 0.71 | RAB9A (0.42) | MAOAACHE | |
| SCHEMBL8206319 | 0.71 | TDP1 (0.55) | BCHECES1METAP1MAOAMAOB | |
| SCHEMBL31638281 | 0.71 | CES1 (0.52) | BCHECES1METAP1MAOAMAOB | |
| SCHEMBL26073771 | 0.71 | BCHE (0.52) | BCHECES1METAP1MAOAACHE | |
| SCHEMBL8217231 | 0.70 | BCHE (0.47) | BCHECES1METAP1CES2MAOA | |
| SCHEMBL1512575 | 0.70 | METAP1 (0.70) | BCHECES1METAP1CES2MIF | |
| SCHEMBL1512594 | 0.70 | ALDH1A1 (0.50) | BCHECES1METAP1MAOAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127189-A | CONTACTING WITH A 1,2-INDANEDIONE DERIVATIVE, MEASURING ABSORBANCE OR FLUORESCENCE OF PRODUCT FORMED, AND COMPARING TO STANDARDS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2000-10-03 | — | — | US | claimed |
| WO-1998020344-A1 | COMPOSITIONS AND METHODS FOR DETECTION OF AN AMINE COMPOUND | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1998-05-14 | — | — | WO | claimed |
| US-6127189-A | CONTACTING WITH A 1,2-INDANEDIONE DERIVATIVE, MEASURING ABSORBANCE OR FLUORESCENCE OF PRODUCT FORMED, AND COMPARING TO STANDARDS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2000-10-03 | — | — | US | disclosed |
| WO-1998020344-A1 | COMPOSITIONS AND METHODS FOR DETECTION OF AN AMINE COMPOUND | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1998-05-14 | — | — | WO | disclosed |