SCHEMBL8204769

SCHEMBL8204769

CCOc1ccc(C(C)=O)cc1Cl

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CREBBP Q92793 3/20 0.66
RORC P51449 1/20 0.65
ALDH1A1 P00352 3/20 0.59
MAPK1 P28482 1/20 0.59
POLB P06746 2/20 0.58
MEN1 O00255 2/20 0.58
KMT2A Q03164 2/20 0.58
MRGPRX4 Q96LA9 1/20 0.58
LMNA P02545 1/20 0.58
GAA P10253 1/20 0.58
MCL1 Q07820 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
NPC1 O15118 3/20 0.58
RAB9A P51151 3/20 0.58
SMN1; SMN2 Q16637 3/20 0.58
NFKB1 P19838 1/20 0.58
NFKB2 Q00653 1/20 0.58
RELA Q04206 1/20 0.58
ADRB2 P07550 1/20 0.56
MAPT P10636 4/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9145276 0.87 CREBBP (0.55) CREBBPRORCALDH1A1MAPK1POLB
SCHEMBL2964617 0.86 CREBBP (0.61) CREBBPRORCALDH1A1MAPK1MEN1
SCHEMBL566498 0.86 POLB (0.70) RORCALDH1A1POLBMEN1KMT2A
SCHEMBL11808755 0.86 POLB (0.58) CREBBPRORCALDH1A1MAPK1POLB
SCHEMBL16959981 0.86 RORC (0.55) CREBBPRORCALDH1A1MAPK1POLB
SCHEMBL4464186 0.85 MAPK1 (0.67) CREBBPRORCALDH1A1MAPK1POLB
SCHEMBL2007531 0.85 ALDH1A1 (0.54) CREBBPRORCALDH1A1MAPK1MEN1
SCHEMBL16954838 0.84 POLB (0.56) CREBBPRORCALDH1A1MAPK1POLB
SCHEMBL29463757 0.84 CREBBP (0.72) CREBBPALDH1A1MAPK1POLBMEN1
SCHEMBL3034164 0.84 CREBBP (0.72) CREBBPALDH1A1MAPK1POLBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6093851-A N-(α-alkylbenzylidene)-α-phenylalkylamine, its use and process for producing the same and process for producing intermediate therefor SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2000-07-25 US disclosed
US-5945382-A AND A METHOD OF THEIR PREPARATION BY CHLORINATION OF AN INTERMEDIATE ARYLPYRAZOLE; PROTECTION AGAINST FUNGAL DISEASES IN TOMATO, RICE, AND WHEAT PLANTS RHONE-POULENC AGROCHIMIE (FR) 1999-08-31 US disclosed
EP-0735018-B1 N-(alpha-alkylbenzylidene)-alpha-phenylalkylamine, its use and process for producing the same and process for producing intermediate therefor SUMITOMO CHEMICAL CO (JP) 1999-07-21 EP disclosed
US-5739401-A N-(α-alkylbenzylidene)-α-phenylalkylamine, its use and process for producing the same and process for producing intermediate therefor SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-04-14 US disclosed
EP-0735018-A1 N-(alpha-alkylbenzylidene)-alpha-phenylalkylamine, its use and process for producing the same and process for producing intermediate therefor SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-10-02 EP disclosed