Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8210568 | 0.89 | HPGD (0.39) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL8173986 | 0.83 | DAO (0.38) | DAOLMNAALDH1A1L3MBTL1MAPT | |
| SCHEMBL7848694 | 0.82 | LMNA (0.41) | DAOLMNAALDH1A1L3MBTL1MAPT | |
| SCHEMBL7851082 | 0.82 | DHODH (0.32) | — | |
| SCHEMBL7852959 | 0.82 | KDM4E (0.34) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL7852090 | 0.81 | GRIN1 (0.37) | ALDH1A1KMT2AMEN1SMN1; SMN2TDP1 | |
| SCHEMBL7853459 | 0.80 | CYP1A2 (0.34) | ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL6089258 | 0.80 | KMT2A (0.41) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL7854087 | 0.80 | ACKR3 (0.36) | — | |
| SCHEMBL7849258 | 0.80 | GRIN1 (0.32) | KMT2AMEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000061563-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-10-19 | — | — | WO | disclosed |