SCHEMBL8210568

Cc1cc(C)cc(C(=O)c2[nH]c(=O)[nH]c(=O)c2C(C)C)c1.Cc1cc(C)cc(C(=O)c2c(C(C)C)c(=O)[nH]c(=O)n2Cc2ccccc2)c1

nearest known ligand 0.56

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	HPGD	P15428	2/20	0.39

▸	TSHR	P16473	2/20	0.39

▸	KMT2A	Q03164	2/20	0.39

▸	KDM4E	B2RXH2	1/20	0.39

▸	MEN1	O00255	1/20	0.39

▸	PSMD14	O00487	1/20	0.39

▸	HTT	P42858	1/20	0.39

▸	POLB	P06746	2/20	0.36

▸	MAPT	P10636	1/20	0.36

▸	ALDH1A1	P00352	1/20	0.36

▸	HSD17B10	Q99714	1/20	0.36

▸	CYP3A4	P08684	1/20	0.35

▸	CYP2C9	P11712	1/20	0.35

▸	PKM	P14618	1/20	0.35

▸	CYP2C19	P33261	1/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL6089258	0.92	KMT2A (0.41)	HPGDTSHRKMT2AKDM4EMEN1
SCHEMBL7849258	0.89	GRIN1 (0.32)	KMT2AMEN1
SCHEMBL8204878	0.89	DAO (0.37)	KMT2AKDM4EMEN1MAPTALDH1A1
SCHEMBL7851716	0.88	NR3C1 (0.37)	POLB
SCHEMBL7851082	0.87	DHODH (0.32)	—
SCHEMBL7847117	0.86	DHODH (0.35)	HPGDTSHRKMT2AMEN1ALDH1A1
SCHEMBL7853459	0.85	CYP1A2 (0.34)	HPGDTSHRKMT2AKDM4EMEN1
SCHEMBL7854087	0.85	ACKR3 (0.36)	—
SCHEMBL6088109	0.84	KMT2A (0.37)	HPGDTSHRKMT2AKDM4EMEN1
SCHEMBL6634103	0.84	KMT2A (0.38)	HPGDKMT2AKDM4EMEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2000061563-A1	ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF	SAMJIN PHARMACEUTICAL CO., LTD. (KR)	2000-10-19	—	—	WO	disclosed