Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA3 | P07451 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10687747 | 0.98 | LOXL2 (0.53) | LOXL2ALDH1A1HTR2ATAAR1LMNA | |
| SCHEMBL701757 | 0.83 | ALDH1A1 (0.50) | LOXL2ALDH1A1HTR2ATAAR1LMNA | |
| SCHEMBL18833848 | 0.82 | LOXL2 (0.53) | LOXL2ALDH1A1TDP1TSHRCYP1A2 | |
| SCHEMBL942066 | 0.82 | LOXL2 (0.53) | LOXL2ALDH1A1TDP1TSHRCYP1A2 | |
| Hydrochloric Acid SCHEMBL1820970 | 0.80 | LOXL2 (0.52) | LOXL2ALDH1A1TDP1TSHRCYP1A2 | |
| Hydrochloric Acid SCHEMBL11740245 | 0.80 | LOXL2 (0.52) | LOXL2ALDH1A1TDP1TSHRCYP1A2 | |
| SCHEMBL334438 | 0.80 | ALDH1A1 (0.68) | LOXL2ALDH1A1TAAR1TDP1TSHR | |
| SCHEMBL4942727 | 0.80 | ALDH1A1 (0.68) | LOXL2ALDH1A1TAAR1TDP1TSHR | |
| SCHEMBL6554390 | 0.80 | LOXL2 (0.52) | LOXL2ALDH1A1TAAR1TDP1TSHR | |
| SCHEMBL7150447 | 0.80 | ALDH1A1 (0.68) | LOXL2ALDH1A1TAAR1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6150335-A | TREATMENT FOR PAIN | ASTRA AB (SE) | 2000-11-21 | — | — | US | disclosed |
| EP-0946588-A1 | USE OF DIPEPTIDE DERIVATIVES | Astra Aktiebolag (publ) (SE) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998028327-A1 | NEW USE OF DIPEPTIDE DERIVATIVES | ASTRA AKTIEBOLAG (PUBL) (SE) | 1998-07-02 | — | — | WO | disclosed |