SCHEMBL820501

SCHEMBL820501

CC(C)COCC(C(=O)Cl)C1CCCC1

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.33
RAB9A P51151 2/20 0.33
GAA P10253 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
HIF1A Q16665 1/20 0.31
DPP4 P27487 1/20 0.31
CA12 O43570 2/20 0.30
CA1 P00915 2/20 0.30
CA2 P00918 2/20 0.30
MMP2 P08253 2/20 0.30
CA9 Q16790 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL819304 0.98 EPHX1 (0.36) EPHX1RAB9AGAASMN1; SMN2CYP2C9
SCHEMBL819818 0.84 ALDH1A1 (0.33) EPHX1CYP2C9CYP2C19HIF1AMMP2
SCHEMBL818669 0.83 ALDH1A1 (0.35) EPHX1CYP2C9CYP2C19HIF1AMMP2
SCHEMBL820370 0.80 NPSR1 (0.38) EPHX1SMN1; SMN2CYP2C9CYP2C19HIF1A
SCHEMBL888550 0.80 CYP2D6 (0.40) RAB9AGAASMN1; SMN2
SCHEMBL888578 0.79 ALDH1A1 (0.42) EPHX1GAASMN1; SMN2
SCHEMBL819198 0.79 NPSR1 (0.41) EPHX1SMN1; SMN2CYP2C9CYP2C19HIF1A
SCHEMBL27823560 0.76 CYP2C9 (0.34) EPHX1CYP2C9CYP2C19HIF1A
SCHEMBL18338078 0.74 SHBG (0.43) EPHX1CYP2C9CYP2C19HIF1ACA12
SCHEMBL819751 0.73 HSD11B1 (0.33) EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102250266-B Process for producing solid catalyst component for olefin polymerization SUMITOMO CHEMICAL CO., LTD. (JP) 2014-10-22 CN disclosed
CN-103289210-A Polypropylene resin composition and molded body containing same SUMITOMO CHEMICAL CO 2013-09-11 CN disclosed
US-8288488-B2 Process for producing solid catalyst component for olefin polymerization SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-16 US disclosed
CN-102250266-A Process for producing solid catalyst component for olefin polymerization SUMITOMO CHEMICAL CO 2011-11-23 CN disclosed
US-20110269929-A1 PROCESS FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-03 US disclosed
US-20110269928-A1 PROCESS FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-03 US disclosed