Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.30 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14289031 | 0.85 | POLB (0.35) | TSHRRAB9AALDH1A1TFPI2AKR1C1 | |
| SCHEMBL14289077 | 0.80 | TSHR (0.33) | TSHRRAB9AALDH1A1TFPI2AKR1C1 | |
| SCHEMBL5098846 | 0.80 | TSHR (0.33) | TSHRRAB9AALDH1A1TFPI2AKR1C1 | |
| SCHEMBL8205182 | 0.72 | CA2 (0.33) | — | |
| SCHEMBL7663156 | 0.67 | POLB (0.70) | TSHRRAB9AALDH1A1TFPI2AKR1C1 | |
| SCHEMBL19446985 | 0.67 | HSD17B10 (0.34) | TSHRRAB9AALDH1A1TFPI2AKR1C1 | |
| SCHEMBL9513526 | 0.66 | ALDH1A1 (0.45) | TSHRRAB9AALDH1A1MAPT | |
| SCHEMBL14289057 | 0.66 | POLB (0.38) | TSHRRAB9AALDH1A1TFPI2AKR1C1 | |
| SCHEMBL5996019 | 0.64 | TSHR (0.35) | TSHRRAB9ATFPI2AKR1C1 | |
| SCHEMBL5996015 | 0.64 | TSHR (0.35) | TSHRRAB9ATFPI2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973780-A1 | ANTIBACTERIAL SUBSTITUTED 7-ACYLAMINO -3-(METHYLHYDRAZONO) METHYL-CEPHALOSPORINS AND INTERMEDIATES | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998043981-A1 | ANTIBACTERIAL SUBSTITUTED 7-ACYLAMINO-3-(METHYLHYDRAZONO)METHYL -CEPHALOSPORINS AND INTERMEDIATES | BIOCHEMIE GESELLSCHAFT MBH (AT) | 1998-10-08 | — | — | WO | disclosed |