Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAA2 | P54646 | 4/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 7/20 | 0.36 |
| ▸ | DRD2 | P14416 | 5/20 | 0.36 |
| ▸ | DRD4 | P21917 | 4/20 | 0.36 |
| ▸ | DRD3 | P35462 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8198981 | 0.86 | PRKAA2 (0.44) | PRKAA2 | |
| SCHEMBL12853174 | 0.77 | PRKAA2 (0.45) | PRKAA2DRD2DRD4DRD3KDM4E | |
| SCHEMBL8209567 | 0.75 | KDM4E (0.47) | KDM4EALDH1A1HIF1A | |
| SCHEMBL8207035 | 0.72 | MEN1 (0.42) | ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL8208820 | 0.71 | HPGD (0.45) | ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL31042527 | 0.64 | DRD4 (0.51) | USP30DRD2DRD4DRD3KDM4E | |
| SCHEMBL8204060 | 0.64 | HSD11B1 (0.41) | PRKAA2 | |
| SCHEMBL8211223 | 0.63 | GPR119 (0.50) | PRKAA2ALDH1A1 | |
| SCHEMBL519202 | 0.63 | PRKAA2 (1.00) | PRKAA2 | |
| SCHEMBL8212238 | 0.63 | F10 (0.49) | PRKAA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008082487-A2 | NOVEL JNK INHIBITORS | SCHERING CORPORATION (US) | 2008-07-10 | — | — | WO | disclosed |