SCHEMBL8205835

SCHEMBL8205835

CCNC(=O)[C@@H](Cc1ccccc1)N(C)C(=O)C(CC(N)=O)c1ccc2ccccc2c1

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 2/20 0.40
GHSR Q92847 2/20 0.39
CYP2D6 P10635 4/20 0.38
SLC6A2 P23975 4/20 0.38
SLC6A4 P31645 4/20 0.38
SLC6A3 Q01959 4/20 0.38
KCNH2 Q12809 3/20 0.38
CYP3A4 P08684 3/20 0.38
TNF P01375 1/20 0.38
TPH1 P17752 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6324651 0.80 PPARG (0.45) GHSR
SCHEMBL6324655 0.77 MME (0.47) GHSR
SCHEMBL6320189 0.70 FCER2 (0.44) GHSR
SCHEMBL28605610 0.69 EPHX1 (0.68) UTS2RCYP2D6SLC6A2SLC6A4SLC6A3
SCHEMBL8100511 0.69 MC4R (0.50) GHSR
SCHEMBL8715806 0.69 FCER2 (0.52) GHSR
SCHEMBL27562948 0.69 GHSR (0.41) GHSR
SCHEMBL8905746 0.67 GHSR (0.48) GHSR
SCHEMBL8174004 0.67 MC4R (0.58)
SCHEMBL15553975 0.67 EPHX1 (0.46) UTS2RCYP2D6SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6127391-A A PEPTIDE MIMETIC COMPOUND FOR STIMULATING THE RELEASE OF GROWTH HORMONE FROM THE PITUITARY NOVO NORDISK A/S (DK) 2000-10-03 US disclosed