Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 8/20 | 0.50 |
| ▸ | MC3R | P41968 | 8/20 | 0.50 |
| ▸ | MC5R | P33032 | 2/20 | 0.50 |
| ▸ | FCER2 | P06734 | 2/20 | 0.48 |
| ▸ | GHSR | Q92847 | 2/20 | 0.47 |
| ▸ | MC1R | Q01726 | 6/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4426088 | 0.87 | FCER2 (0.53) | FCER2GHSRMMP9MMP8 | |
| SCHEMBL4427112 | 0.87 | FCER2 (0.53) | FCER2GHSRMMP9MMP8 | |
| SCHEMBL6317992 | 0.87 | FCER2 (0.53) | FCER2GHSRMMP9MMP8 | |
| SCHEMBL8174004 | 0.84 | MC4R (0.58) | MC4RMC3RMC5RMC1R | |
| SCHEMBL7061723 | 0.82 | GHSR (0.47) | MC4RMC3RFCER2GHSRMC1R | |
| SCHEMBL4428281 | 0.81 | GHSR (0.49) | FCER2GHSRMMP9MMP8 | |
| SCHEMBL7368069 | 0.81 | GHSR (0.49) | FCER2GHSRMMP9MMP8 | |
| SCHEMBL7895834 | 0.81 | MMP2 (0.50) | — | |
| SCHEMBL7404019 | 0.81 | MMP2 (0.50) | — | |
| SCHEMBL6318200 | 0.81 | GHSR (0.42) | MC4RMC3RFCER2GHSRMC1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060190-A1 | NEW SALT FORMS OF (2E)- 5-AMINO-5- METHYLHEX-2- ENOIC ACID N-METHYL-N-((1R)-1-(N- METHYL-N-((1R)-1-(METHYLCARBAMOYL)-2- PHENYLETHYL)CARBAMOYL)-2- (2-NAPHTYL)ETHYL)AMIDE | NOVO NORDISK A/S (DK) | 2000-12-20 | — | — | EP | claimed |
| WO-1999045029-A1 | NEW SALT FORMS OF (2E)- 5-AMINO-5- METHYLHEX-2- ENOIC ACID N-METHYL-N-((1R)-1-(N- METHYL-N-((1R)-1-(METHYLCARBAMOYL)-2- PHENYLETHYL)CARBAMOYL)-2- (2-NAPHTYL)ETHYL)AMIDE | NOVO NORDISK A/S (DK) | 1999-09-10 | — | — | WO | claimed |