Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 3/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 3/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.39 |
| ▸ | CTSS | P25774 | 2/20 | 0.39 |
| ▸ | FCER2 | P06734 | 2/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | CPA1 | P15085 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 2/20 | 0.38 |
| ▸ | MC5R | P33032 | 2/20 | 0.38 |
| ▸ | MC3R | P41968 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6318464 | 0.89 | CTSB (0.45) | GHSRMMP9MMP8TACR1CTSB | |
| SCHEMBL6316677 | 0.88 | GHSR (0.45) | GHSRMMP9MMP8TACR1CTSB | |
| SCHEMBL6318261 | 0.84 | GHSR (0.58) | GHSRMMP9MMP8TACR1CTSB | |
| SCHEMBL6318245 | 0.84 | GHSR (0.58) | GHSRMMP9MMP8TACR1CTSB | |
| SCHEMBL8905882 | 0.84 | GHSR (0.49) | GHSRTACR1CTSBCTSSCTSK | |
| SCHEMBL3270974 | 0.83 | GHSR (0.51) | GHSRMMP9MMP8TACR1CTSB | |
| SCHEMBL7065323 | 0.83 | MMP9 (0.51) | GHSRMMP9MMP8TACR1MC4R | |
| SCHEMBL3266716 | 0.82 | GHSR (0.47) | GHSRMMP9MMP8TACR1CTSB | |
| SCHEMBL7061723 | 0.82 | GHSR (0.47) | GHSRMMP9MMP8TACR1FCER2 | |
| SCHEMBL6321276 | 0.80 | GHSR (0.57) | GHSRCTSBCTSSCTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997023508-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1997-07-03 | — | — | WO | disclosed |