Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 5/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8209850 | 0.86 | RECQL (0.41) | SMN1; SMN2ALDH1A1HSD17B10LMNAHTT | |
| SCHEMBL7282045 | 0.85 | TRPA1 (0.35) | TRPA1CA12CA9ALDH1A1KDM4E | |
| SCHEMBL9933270 | 0.79 | TRPA1 (0.43) | TRPA1SMN1; SMN2MAPTHSD17B10LMNA | |
| SCHEMBL25341094 | 0.70 | TRPA1 (0.39) | TRPA1CA12CA9ALDH1A1KDM4E | |
| SCHEMBL27540000 | 0.69 | TRPA1 (0.43) | TRPA1CA12CA9SMN1; SMN2MAPT | |
| SCHEMBL10499941 | 0.69 | TRPA1 (0.40) | TRPA1CA12CA9 | |
| SCHEMBL30616800 | 0.68 | TRPA1 (0.42) | TRPA1CA12CA9SMN1; SMN2ALDH1A1 | |
| SCHEMBL26686704 | 0.68 | TRPA1 (0.42) | TRPA1CA12CA9SMN1; SMN2ALDH1A1 | |
| SCHEMBL7377318 | 0.68 | TRPA1 (0.49) | TRPA1CA12CA9SMN1; SMN2ALDH1A1 | |
| SCHEMBL11660750 | 0.68 | HPGD (0.46) | CA12CA9SMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0979227-A1 | 4,1-BENZOXAZEPINES, THEIR ANALOGUES, AND THEIR USE AS SOMATOSTATIN AGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2000-02-16 | — | — | EP | disclosed |
| WO-1998047882-A1 | 4,1-BENZOXAZEPINES, THEIR ANALOGUES, AND THEIR USE AS SOMATOSTATIN AGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-10-29 | — | — | WO | disclosed |