Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9933270 | 0.77 | TRPA1 (0.43) | SMN1; SMN2HSD17B10LMNAHTTMAPK1 | |
| SCHEMBL27490082 | 0.71 | RECQL (0.41) | RECQLSMN1; SMN2PKMPOLBALDH1A1 | |
| SCHEMBL10499941 | 0.67 | TRPA1 (0.40) | — | |
| SCHEMBL6188489 | 0.67 | SMN1; SMN2 (0.41) | RECQLSMN1; SMN2PKMPOLBALDH1A1 | |
| SCHEMBL68340 | 0.64 | PKM (0.60) | SMN1; SMN2PKMALDH1A1HSD17B10TSHR | |
| SCHEMBL9692782 | 0.64 | ALOX5 (0.40) | RECQLSMN1; SMN2PKMPOLBALDH1A1 | |
| SCHEMBL4818941 | 0.63 | MEN1 (0.61) | POLBALDH1A1LMNA | |
| SCHEMBL27490774 | 0.63 | POLB (0.60) | SMN1; SMN2POLBTSHRLMNAMAPK1 | |
| SCHEMBL112999 | 0.63 | ALDH1A1 (0.68) | SMN1; SMN2PKMALDH1A1TSHRLMNA | |
| SCHEMBL1332625 | 0.63 | ALDH1A1 (0.68) | SMN1; SMN2PKMALDH1A1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0979227-A1 | 4,1-BENZOXAZEPINES, THEIR ANALOGUES, AND THEIR USE AS SOMATOSTATIN AGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2000-02-16 | — | — | EP | disclosed |
| WO-1998047882-A1 | 4,1-BENZOXAZEPINES, THEIR ANALOGUES, AND THEIR USE AS SOMATOSTATIN AGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-10-29 | — | — | WO | disclosed |
| EP-0862562-A1 | BENZOXAZEPINE COMPOUNDS, THEIR PRODUCTION AND USE AS LIPID LOWERING AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1998-09-09 | — | — | EP | disclosed |
| WO-1997010224-A1 | BENZOXAZEPINE COMPOUNDS, THEIR PRODUCTION AND USE AS LIPID LOWERING AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-03-20 | — | — | WO | disclosed |