Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.49 |
| ▸ | CCR3 | P51677 | 2/20 | 0.47 |
| ▸ | TRPV6 | Q9H1D0 | 5/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8205475 | 0.83 | CHRM3 (0.44) | KCNA3TSHR | |
| SCHEMBL4186493 | 0.82 | KCNA3 (0.55) | KCNA3CCR3SIGMAR1DRD4DRD2 | |
| Hydrochloric Acid SCHEMBL10360726 | 0.81 | KCNA3 (0.53) | KCNA3CCR3SIGMAR1DRD4DRD2 | |
| SCHEMBL956111 | 0.77 | KCNA3 (0.49) | KCNA3CCR3SIGMAR1DRD4DRD2 | |
| SCHEMBL956109 | 0.77 | KCNA3 (0.49) | KCNA3CCR3SIGMAR1DRD4DRD2 | |
| SCHEMBL8206412 | 0.77 | ACHE (0.43) | TRPV6RECQLSMN1; SMN2ACHE | |
| SCHEMBL11235320 | 0.76 | KCNA3 (0.50) | KCNA3CCR3SIGMAR1DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL954583 | 0.76 | KCNA3 (0.48) | KCNA3CCR3SIGMAR1DRD4DRD2 | |
| Hydrochloric Acid SCHEMBL954585 | 0.76 | KCNA3 (0.48) | KCNA3CCR3SIGMAR1DRD4DRD2 | |
| SCHEMBL4797625 | 0.76 | SIGMAR1 (0.69) | CCR3TRPV6SIGMAR1RECQLSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0999205-A1 | AMINOCYCLOALKANE COMPOUNDS | Mitsubishi-Tokyo Pharmaceuticals, Inc. (JP) | 2000-05-10 | — | — | EP | disclosed |