Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | FHIT | P49789 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7521891 | 0.88 | HPGD (0.36) | HPGDALDH1A1MAPTGAASMN1; SMN2 | |
| SCHEMBL7524077 | 0.73 | ALDH1A1 (0.39) | HPGDALDH1A1MAPTGAASMN1; SMN2 | |
| SCHEMBL7515278 | 0.73 | HPGD (0.33) | HPGDALDH1A1MAPTGAASMN1; SMN2 | |
| SCHEMBL8930717 | 0.71 | ALDH1A1 (0.39) | HPGDALDH1A1MAPTGAASMN1; SMN2 | |
| Tromethamine SCHEMBL8045821 | 0.69 | ALDH1A1 (0.39) | HPGDALDH1A1MAPTGAASMN1; SMN2 | |
| SCHEMBL8045320 | 0.69 | ALDH1A1 (0.34) | HPGDALDH1A1MAPTGAASMN1; SMN2 | |
| SCHEMBL7514575 | 0.68 | CYP3A4 (0.45) | HPGDALDH1A1MAPTGAASMN1; SMN2 | |
| SCHEMBL12530071 | 0.68 | HPGD (0.45) | HPGDALDH1A1MAPTGAASMN1; SMN2 | |
| SCHEMBL8930693 | 0.66 | ALDH1A1 (0.38) | HPGDALDH1A1MAPTGAASMN1; SMN2 | |
| SCHEMBL8035997 | 0.63 | ALDH1A1 (0.37) | HPGDALDH1A1MAPTGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832054-B1 | HETEROCYCLIC METHYL FREE RADICALS AS IMAGE ENHANCING AGENTS | NYCOMED IMAGING AS (NO) | 2000-12-27 | — | — | EP | disclosed |