Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8206551 | 0.92 | CA2 (0.37) | CA2CA12CA14CA1MAOA | |
| SCHEMBL397677 | 0.84 | CA2 (0.37) | CA2CA12CA14CA1MAOA | |
| SCHEMBL5329667 | 0.83 | CA12 (0.34) | CA2CA12CA14CA1MAOA | |
| SCHEMBL8150221 | 0.79 | CA2 (0.36) | CA2CA12CA14CA1MAOA | |
| SCHEMBL3657317 | 0.76 | CA2 (0.37) | CA2CA12CA14CA1MAOA | |
| SCHEMBL783009 | 0.75 | CA2 (0.41) | CA2CA12CA14CA1MAOA | |
| SCHEMBL27798445 | 0.75 | CA2 (0.36) | CA2CA12CA14CA1MAOA | |
| SCHEMBL28061441 | 0.73 | HDAC6 (0.36) | CA2CA12CA14CA1DGAT1 | |
| SCHEMBL26763529 | 0.73 | DGAT1 (0.33) | CA2CA12CA14CA1MAOA | |
| SCHEMBL29004075 | 0.73 | RECQL (0.36) | CA2CA12CA14MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0794788-A4 | HEPATIC-DIRECTED COMPOUNDS AND REAGENTS FOR PREPARATION THEREOF | NEORX CORP (US) | 2000-05-24 | — | — | EP | disclosed |
| EP-0794788-A1 | HEPATIC-DIRECTED COMPOUNDS AND REAGENTS FOR PREPARATION THEREOF | NEORX CORPORATION (US) | 1997-09-17 | — | — | EP | disclosed |
| WO-1996017613-A1 | HEPATIC-DIRECTED COMPOUNDS AND REAGENTS FOR PREPARATION THEREOF | NEORX CORPORATION (US) | 1996-06-13 | — | — | WO | disclosed |