Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 14/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | GABRP | O00591 | 1/20 | 0.43 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7736190 | 0.91 | NISCH (0.58) | NISCHADRA2AADRA2BADRA2CALDH1A1 | |
| SCHEMBL8189601 | 0.90 | NISCH (0.49) | NISCHADRA2AADRA2BADRA2CALDH1A1 | |
| Hydrochloric Acid SCHEMBL8202804 | 0.89 | NISCH (0.59) | NISCHADRA2AADRA2BADRA2CALDH1A1 | |
| Hydrochloric Acid SCHEMBL8201249 | 0.85 | NISCH (0.44) | NISCHADRA2AADRA2BADRA2CALDH1A1 | |
| Hydrochloric Acid SCHEMBL8199767 | 0.84 | NISCH (0.54) | NISCHADRA2AADRA2BADRA2CALDH1A1 | |
| SCHEMBL8188884 | 0.84 | NISCH (0.58) | NISCHADRA2AADRA2BADRA2CALDH1A1 | |
| SCHEMBL8198751 | 0.83 | NISCH (0.54) | NISCHADRA2AADRA2BADRA2CALDH1A1 | |
| SCHEMBL8204316 | 0.83 | NISCH (0.74) | NISCHADRA2AADRA2BADRA2CMAOB | |
| Hydrochloric Acid SCHEMBL8197103 | 0.82 | LMNA (0.49) | NISCHADRA2AADRA2BADRA2CALDH1A1 | |
| SCHEMBL8189612 | 0.82 | ADRA2A (0.48) | NISCHADRA2AADRA2BADRA2CALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000078726-A1 | IMIDAZOLINE DERIVATIVES FOR THE TREATMENT OF DIABETES, ESPECIALLY TYPE II DIABETES | ELI LILLY AND COMPANY (US) | 2000-12-28 | — | — | WO | disclosed |