Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.36 |
| ▸ | UNG | P13051 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.35 |
| ▸ | P4HB | P07237 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8210100 | 0.89 | P4HB (0.38) | MRGPRX4MEN1KMT2ATTRP4HB | |
| SCHEMBL8205809 | 0.82 | FNTA (0.46) | ALDH1A1 | |
| SCHEMBL8206086 | 0.81 | GAA (0.43) | NR4A2TRPM8UNGMEN1KMT2A | |
| SCHEMBL7708946 | 0.73 | TTR (0.39) | NR4A2MRGPRX4UNGMEN1KMT2A | |
| SCHEMBL8207394 | 0.72 | FNTA (0.39) | — | |
| SCHEMBL8273539 | 0.71 | GAA (0.43) | MRGPRX4MEN1KMT2AP4HBALDH1A1 | |
| SCHEMBL7245883 | 0.68 | CYP19A1 (0.47) | POLBL3MBTL1 | |
| SCHEMBL7245884 | 0.68 | CYP19A1 (0.47) | POLBL3MBTL1 | |
| SCHEMBL7708970 | 0.68 | CYP19A1 (0.47) | POLBL3MBTL1 | |
| SCHEMBL8205834 | 0.68 | GAA (0.42) | NR4A2ALDH1A1POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975603-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | ZENECA LIMITED (GB) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998032741-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | ZENECA LIMITED (GB) | 1998-07-30 | — | — | WO | disclosed |