Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25294321 | 0.83 | TSHR (0.36) | TSHRCYP2C19 | |
| SCHEMBL881429 | 0.81 | — | — | |
| Nitrous Acid SCHEMBL597561 | 0.77 | TSHR (0.34) | TSHRCYP2C19 | |
| SCHEMBL3318734 | 0.75 | — | — | |
| Nitric Acid SCHEMBL5697160 | 0.75 | CA5A (0.40) | CA5ACA5BTSHRCYP2C19 | |
| Nitric Acid SCHEMBL5697157 | 0.73 | CA5A (0.38) | CA5ACA5BTSHRCYP2C19 | |
| Nitric Acid SCHEMBL8206708 | 0.72 | CA5A (0.33) | CA5ACA5B | |
| SCHEMBL3313074 | 0.69 | — | — | |
| Cyclohexane SCHEMBL8006197 | 0.69 | CA5A (0.73) | CA5ACA5BTSHR | |
| Cyclohexane SCHEMBL2019979 | 0.69 | CA5A (0.73) | CA5ACA5BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6160195-A | Use of reagents to convert chrysotile and amosite asbestos used as insulation or protection for metal surfaces | BROOKHAVEN SCIENCE ASSOCIATES (US) | 2000-12-12 | — | — | US | disclosed |