Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 3/20 | 0.43 |
| ▸ | CTSK | P43235 | 3/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | ACKR3 | P25106 | 10/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8200884 | 0.99 | RORC (0.47) | RORCCTSSCTSKCTSLCTSB | |
| SCHEMBL3179697 | 0.92 | CTSS (0.52) | RORCCTSSCTSKCTSLCTSB | |
| SCHEMBL3159800 | 0.91 | CTSS (0.52) | RORCCTSSCTSKCTSLCTSB | |
| SCHEMBL8201079 | 0.91 | CTSS (0.53) | RORCCTSSCTSKCTSLCTSB | |
| SCHEMBL8193466 | 0.90 | CTSS (0.44) | RORCCTSSCTSKCTSLCTSB | |
| SCHEMBL14142826 | 0.88 | CTSS (0.46) | RORCCTSSCTSKCTSLCTSB | |
| Trifluoroacetic Acid SCHEMBL3175330 | 0.88 | CTSS (0.48) | RORCCTSSCTSKCTSLCTSB | |
| Trifluoroacetic Acid SCHEMBL3172970 | 0.87 | CTSS (0.48) | RORCCTSSCTSKCTSLCTSB | |
| SCHEMBL8201088 | 0.84 | CTSS (0.59) | CTSSCTSKCTSLCTSBPRKAA2 | |
| SCHEMBL14142824 | 0.84 | ACVR1 (0.38) | RORCCTSSCTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008052934-A1 | NOVEL SUBSTITUTED PYRIMIDINES AS CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2008-05-08 | — | — | WO | disclosed |