Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 4/20 | 0.58 |
| ▸ | MMP3 | P08254 | 4/20 | 0.58 |
| ▸ | MMP7 | P09237 | 3/20 | 0.58 |
| ▸ | MMP13 | P45452 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PKLR | P30613 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8206472 | 0.96 | LMNA (0.55) | MMP1MMP3MMP7MMP13HTT | |
| SCHEMBL8211439 | 0.96 | LMNA (0.55) | MMP1MMP3MMP7MMP13HTT | |
| SCHEMBL8207819 | 0.88 | MMP1 (0.59) | MMP1MMP3MMP7MMP13HTT | |
| SCHEMBL8207084 | 0.87 | MMP1 (0.58) | MMP1MMP3MMP7MMP13HTT | |
| SCHEMBL8212961 | 0.84 | TSHR (0.58) | MMP1MMP3MMP7MMP13MMP9 | |
| SCHEMBL8209735 | 0.81 | MMP1 (0.55) | MMP1MMP3MMP7MMP13HTT | |
| SCHEMBL8206916 | 0.81 | MMP1 (0.64) | MMP1MMP3MMP7MMP13HTT | |
| SCHEMBL8199984 | 0.81 | MMP1 (0.60) | MMP1MMP3MMP7MMP13MMP9 | |
| SCHEMBL16254914 | 0.81 | PSEN1 (0.69) | MMP1MMP3MMP7MMP13HTT | |
| SCHEMBL13037004 | 0.77 | PSEN1 (0.71) | MMP1MMP3MMP7MMP13HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121272-A | Bidentate metalloprotease inhibitors | THE PROCTER & GAMBLE COMPANY (US) | 2000-09-19 | — | — | US | disclosed |