Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MMP1 | P03956 | 3/20 | 0.53 |
| ▸ | MMP3 | P08254 | 3/20 | 0.53 |
| ▸ | MMP7 | P09237 | 2/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | MMP13 | P45452 | 1/20 | 0.53 |
| ▸ | HCRTR1 | O43613 | 7/20 | 0.53 |
| ▸ | HCRTR2 | O43614 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | PKLR | P30613 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8211439 | 1.00 | LMNA (0.55) | LMNAMMP1MMP3MMP7MMP9 | |
| SCHEMBL8206912 | 0.96 | MMP1 (0.58) | LMNAMMP1MMP3MMP7MMP9 | |
| SCHEMBL8207819 | 0.84 | MMP1 (0.59) | LMNAMMP1MMP3MMP7MMP9 | |
| SCHEMBL8207084 | 0.83 | MMP1 (0.58) | LMNAMMP1MMP3MMP7MMP9 | |
| SCHEMBL8212961 | 0.80 | TSHR (0.58) | LMNAMMP1MMP3MMP7MMP9 | |
| SCHEMBL8211642 | 0.77 | MMP2 (0.47) | LMNAMMP1MMP3MMP7MMP9 | |
| SCHEMBL8209735 | 0.77 | MMP1 (0.55) | MMP1MMP3MMP7MMP9MMP13 | |
| SCHEMBL8206916 | 0.77 | MMP1 (0.64) | LMNAMMP1MMP3MMP7MMP9 | |
| SCHEMBL8199984 | 0.77 | MMP1 (0.60) | LMNAMMP1MMP3MMP7MMP9 | |
| SCHEMBL2705855 | 0.77 | MMP1 (0.67) | MMP1MMP3MMP7MMP9MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121272-A | Bidentate metalloprotease inhibitors | THE PROCTER & GAMBLE COMPANY (US) | 2000-09-19 | — | — | US | disclosed |