Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 3/20 | 0.58 |
| ▸ | MMP3 | P08254 | 3/20 | 0.58 |
| ▸ | MMP7 | P09237 | 2/20 | 0.58 |
| ▸ | MMP13 | P45452 | 1/20 | 0.58 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.55 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.55 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.55 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.55 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.55 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8211440 | 0.96 | RAB9A (0.56) | MMP1MMP3MMP7MMP13NPC1 | |
| SCHEMBL6323512 | 0.96 | RAB9A (0.56) | MMP1MMP3MMP7MMP13NPC1 | |
| SCHEMBL13037004 | 0.88 | PSEN1 (0.71) | MMP1MMP3MMP7MMP13PSEN1 | |
| SCHEMBL8207295 | 0.87 | MMP1 (0.61) | MMP1MMP3MMP7MMP13PSEN1 | |
| SCHEMBL6977510 | 0.86 | MMP1 (0.63) | MMP1MMP3MMP7MMP13PSEN1 | |
| SCHEMBL8212965 | 0.85 | TSHR (0.60) | MMP1MMP3MMP7MMP13PSEN1 | |
| SCHEMBL12162069 | 0.85 | NPC1 (0.60) | MMP1MMP3MMP7MMP13PSEN1 | |
| SCHEMBL8210383 | 0.85 | MMP1 (0.56) | MMP1MMP3MMP7MMP13PSEN1 | |
| SCHEMBL8209735 | 0.84 | MMP1 (0.55) | MMP1MMP3MMP7MMP13PSEN1 | |
| SCHEMBL6325815 | 0.83 | RAB9A (0.59) | MMP1MMP3MMP7MMP13HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121272-A | Bidentate metalloprotease inhibitors | THE PROCTER & GAMBLE COMPANY (US) | 2000-09-19 | — | — | US | disclosed |